The Basics
What is Haemophilus Vaccines?
The vaccine provides long-term protection from Haemophilus influenzae type b.
Brand names for Haemophilus Vaccines
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How Haemophilus Vaccines is classified
Vaccines
Haemophilus Vaccines During Pregnancy
Haemophilus Vaccines pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Haemophilus Vaccines while pregnant
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Taking Haemophilus Vaccines While Breastfeeding
What are recommendations for lactation if you're taking Haemophilus Vaccines?
Although there is some conflicting information on the effect of breastfeeding on infants’ antibody response to Haemophilus influenzae type b vaccines, there is no evidence that breastfeeding reduces protection against the disease. The Centers for Disease Control and Prevention and several health professional organizations state that vaccines given to a nursing mother do not affect the safety of breastfeeding for mothers or infants and that breastfeeding is not a contraindication to the Haemophilus influenzae vaccine.[1][2][3] Breastfeeding alone appears to increase antibodies against Haemophilus influenzae and reduce the incidence of Haemophilus influenzae type b meningitis.[4][5][6] Breastfeeding also appears to reduce infant side effects associated with routine childhood immunization. Breastfed infants should be vaccinated according to the routine recommended schedules.
Maternal / infant drug levels
Although there is some conflicting information on the effect of breastfeeding on infants’ antibody response to Haemophilus influenzae type b vaccines, there is no evidence that breastfeeding reduces protection against the disease. The Centers for Disease Control and Prevention and several health professional organizations state that vaccines given to a nursing mother do not affect the safety of breastfeeding for mothers or infants and that breastfeeding is not a contraindication to the Haemophilus influenzae vaccine.[1][2][3] Breastfeeding alone appears to increase antibodies against Haemophilus influenzae and reduce the incidence of Haemophilus influenzae type b meningitis.[4][5][6] Breastfeeding also appears to reduce infant side effects associated with routine childhood immunization. Breastfed infants should be vaccinated according to the routine recommended schedules.
Possible effects of Haemophilus Vaccines on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Haemophilus Vaccines
None listed
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. General recommendations on immunization — recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2011;60 (RR-2):1-64. PMID: 21293327
2. Gruslin A, Steben M, Halperin S et al. Immunization in pregnancy: No. 220, December 2008. Int J Gynaecol Obstet. 2009;105:187-91. PMID: 19367691
3. American Academy of Pediatrics Committee on Infectious Diseases, Kimberlin DW, Brady MT et al. Red Book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics. 2015.
4. Silfverdal SA, Bodin L, Ulanova M et al. Expression of idiotypic antibodies-1 and -2 and breastfeeding in relation to antibody levels against Haemophilus influenzae type b in children. Scand J Immunol. 2006;63:371-5. PMID: 16640661
5. Silfverdal SA, Bodin L, Olcen P. Protective effect of breastfeeding: an ecologic study of Haemophilus influenzae meningitis and breastfeeding in a Swedish population. Int J Epidemiol. 1999;28:152-6. PMID: 10195681
6. Silfverdal SA, Bodin L, Hugosson S et al. Protective effect of breastfeeding on invasive Haemophilus influenzae infection: a case-control study in Swedish preschool children. Int J Epidemiol. 1997;26:443-50. PMID: 9169183
7. Insel RA, Amstey M, Pichichero ME. Postimmunization antibody to the Haemophilus influenzae type b capsule in breast milk. J Infect Dis. 1985;152:407-8. PMID: 3875665
8. Pisacane A, Continisio P, Palma O et al. Breastfeeding and risk for fever after immunization. Pediatrics. 2010;125:e1448-52. PMID: 20478932
9. Lopez-Alarcon M, Garza C, Habicht JP et al. Breastfeeding attenuates reductions in energy intake induced by a mild immunologic stimulus represented by DPTH immunization: possible roles of interleukin-1beta, tumor necrosis factor-alpha and leptin. J Nutr. 2002;132:1293-8. PMID: 12042449
10. Pabst HF, Spady DW. Effect of breast-feeding on antibody response to conjugate vaccine. Lancet. 1990;336:269-70. PMID: 1973970
11. Silfverdal SA, Ekholm L, Bodin L. Breastfeeding enhances the antibody response to Hib and pneumococcal serotype 6B and 14 after vaccination with conjugate vaccines. Vaccine. 2006;25:1497-502. PMID: 17097198
12. Scheifele D, Bjornson GJ, Guasparini R et al. Breastfeeding and antibody responses to routine vaccination in infants. Lancet. 1992;340:1406. PMID: 1360102
13. Decker MD, Edwards KM, Bradley R, Palmer P. Comparative trial in infants of four conjugate haemophilus influenzae type b vaccines. J Pediatr. 1992;120:184-9. PMID: 1735812
14. Hawkes JS, Makrides M, Roberton DM, Gibson RA. Responses to immunisation with Hib conjugate vaccine in Australian breastfed and formula-fed infants. J Paediatr Child Health. 2007;43:597-600. PMID: 17688643
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
