The Basics
What is Capreomycin?
Used for the treatment of active tuberculosis (TB).
Brand names for Capreomycin
Capastat Sulfate
How Capreomycin is classified
Anti-Infective Agents, Antibacterial Agents, Antitubercular Agents
Capreomycin During Pregnancy
Capreomycin pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Capreomycin while pregnant
Capastat Sulfate has been shown to be teratogenic in rats when given in doses 3 ¬Ω times the human dose. There are no adequate and well-controlled studies in pregnant women. Capastat Sulfate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus (see BOXED WARNINGS and Animal Pharmacology).
Taking Capreomycin While Breastfeeding
What are recommendations for lactation if you're taking Capreomycin?
Developmental problems have been reported in two infants exposed to capreomycin in breastmilk; however, their mothers were also exposed to several drugs during pregnancy and during breastfeeding, so the problems cannot necessarily be attributed to capreomycin. Because capreomycin is not orally absorbed it is unlikely to adversely affect the breastfed infant.
Maternal / infant drug levels
Developmental problems have been reported in two infants exposed to capreomycin in breastmilk; however, their mothers were also exposed to several drugs during pregnancy and during breastfeeding, so the problems cannot necessarily be attributed to capreomycin. Because capreomycin is not orally absorbed it is unlikely to adversely affect the breastfed infant.
Possible effects of Capreomycin on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Capreomycin
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Drobac PC, del Castillo H, Sweetland A et al. Treatment of multidrug-resistant tuberculosis during pregnancy: long-term follow-up of 6 children with intrauterine exposure to second-line agents. Clin Infect Dis. 2005;40:1689-92. PMID: 15889370
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
