The Basics

What is Ferumoxides?

Indicated for the treatment of iron deficiency anemia in adult patients with chronic kidney disease (CKD).

Brand names for Ferumoxides

Feridex I.V.

How Ferumoxides is classified

Contrast Media, Diagnostic Agents

Ferumoxides During Pregnancy

Ferumoxides pregnancy category

Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Ferumoxides while pregnant

Feridex I.V. (ferumoxides injectable solution) is teratogenic in rabbits at all studied doses. The smallest dose studied was approximately six times the clinical dose when normalized to body surface area. Adequate and well controlled studies were not conducted in pregnant women. Feridex I.V. (ferumoxides injectable solution) should be used during pregnancy only if the potential benefit justifies the potential risk.

Taking Ferumoxides While Breastfeeding

What are recommendations for lactation if you're taking Ferumoxides?

Ferumoxides is a complex of iron oxide and dextran, similar to iron dextran. It is not expected to pose a toxic risk to a nursing infant. However, because there is no published experience with ferumoxides during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.

Maternal / infant drug levels

Ferumoxides is a complex of iron oxide and dextran, similar to iron dextran. It is not expected to pose a toxic risk to a nursing infant. However, because there is no published experience with ferumoxides during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.

Possible effects of Ferumoxides on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Ferumoxides

Gadopentetate.

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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