The Basics
What is Ferumoxides?
Indicated for the treatment of iron deficiency anemia in adult patients with chronic kidney disease (CKD).
Brand names for Ferumoxides
Feridex I.V.
How Ferumoxides is classified
Contrast Media, Diagnostic Agents
Ferumoxides During Pregnancy
Ferumoxides pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Ferumoxides while pregnant
Feridex I.V. (ferumoxides injectable solution) is teratogenic in rabbits at all studied doses. The smallest dose studied was approximately six times the clinical dose when normalized to body surface area. Adequate and well controlled studies were not conducted in pregnant women. Feridex I.V. (ferumoxides injectable solution) should be used during pregnancy only if the potential benefit justifies the potential risk.
Taking Ferumoxides While Breastfeeding
What are recommendations for lactation if you're taking Ferumoxides?
Ferumoxides is a complex of iron oxide and dextran, similar to iron dextran. It is not expected to pose a toxic risk to a nursing infant. However, because there is no published experience with ferumoxides during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
Maternal / infant drug levels
Ferumoxides is a complex of iron oxide and dextran, similar to iron dextran. It is not expected to pose a toxic risk to a nursing infant. However, because there is no published experience with ferumoxides during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
Possible effects of Ferumoxides on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Ferumoxides
Gadopentetate.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.