The Basics

What is Dicloxacillin?

Penicillin medication that can treat infections

Brand names for Dicloxacillin

Dycill

How Dicloxacillin is classified

Anti-Infective Agents, Antibacterial Agents, Penicillins

Dicloxacillin During Pregnancy

Dicloxacillin pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Dicloxacillin while pregnant

N/A

Taking Dicloxacillin While Breastfeeding

What are recommendations for lactation if you're taking Dicloxacillin?

Limited information indicates that dicloxacillin levels in milk are low and are not expected to cause adverse effects in breastfed infants. It is frequently used to treat mastitis in nursing mothers.[1][2][3] Occasionally disruption of the infant’s gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. Dicloxacillin is acceptable in nursing mothers.

Maternal / infant drug levels

Limited information indicates that dicloxacillin levels in milk are low and are not expected to cause adverse effects in breastfed infants. It is frequently used to treat mastitis in nursing mothers.[1][2][3] Occasionally disruption of the infant’s gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. Dicloxacillin is acceptable in nursing mothers.

Possible effects of Dicloxacillin on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Dicloxacillin

(Mastitis) Cephalexin; (Methicillin-resistant Staph. aureus) Doxycycline, Linezolid, Minocycline, Trimethoprim-Sulfamethoxazole, Vancomycin.

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Berth WL, Schauberger CW, Alvarado MA, Mathiason MA. Telephone-based management of lactation mastitis. J Reprod Med. 2009;54:291-4. PMID: 19517693
2. Amir LH. ABM clinical protocol #4: Mastitis, revised March 2014. Breastfeed Med. 2014;9:239-43. PMID: 24911394
3. Berens PD. Breast pain: Engorgement, nipple pain, and mastitis. Clin Obstet Gynecol. 2016;58:902-14. PMID: 26512442
4. Matsuda S. Transfer of antibiotics into maternal milk. Biol Res Pregnancy. 1984;5:57-60. PMID: 6743732

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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