The Basics

What is Caplacizumab?

treats acquired thrombotic thrombocytopenic purpura

Brand names for Caplacizumab

N/A

How Caplacizumab is classified

Antibodies – Monoclonal, Single-Domain Antibodies, No information is available on the clinical use of caplacizumab during breastfeeding. Because caplacizumab is a large protein molecule with a molecular weight of about 28,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant’s gastrointestinal tract. Until more data become available, caplacizumab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.

Caplacizumab During Pregnancy

Caplacizumab pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Caplacizumab while pregnant

N/A

Taking Caplacizumab While Breastfeeding

What are recommendations for lactation if you're taking Caplacizumab?

Maternal / infant drug levels

Possible effects of Caplacizumab on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Caplacizumab

None listed

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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