The Basics
What is Sugammadex?
Indicated for the reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide in adults undergoing surgery.
Brand names for Sugammadex
Bridion
How Sugammadex is classified
Antidotes, Gamma-Cyclodextrins, Neuromuscular Blockade
Sugammadex During Pregnancy
Sugammadex pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Sugammadex while pregnant
N/A
Taking Sugammadex While Breastfeeding
What are recommendations for lactation if you're taking Sugammadex?
No information is available on the clinical use of sugammadex during breastfeeding. Because sugammadex is a large, highly polar molecule with a molecular weight of 2002, the amount in milk is likely to be very low and oral absorption by the infant is unlikely. Sugammadex is acceptable to use during breastfeeding.[1]
Maternal / infant drug levels
No information is available on the clinical use of sugammadex during breastfeeding. Because sugammadex is a large, highly polar molecule with a molecular weight of 2002, the amount in milk is likely to be very low and oral absorption by the infant is unlikely. Sugammadex is acceptable to use during breastfeeding.[1]
Possible effects of Sugammadex on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Sugammadex
Neostigmine.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Schaller SJ, Fink H. Sugammadex as a reversal agent for neuromuscular block: An evidence-based review. Core Evid. 2013;8:57-67. PMID: 24098155
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
