Cyclizine

The Basics

What is Cyclizine?

medication used to treat and prevent nausea, vomiting and dizziness due to motion sickness or vertigo. It may also be used for nausea after general anaesthesia or that which developed from opioid use

Brand names for Cyclizine

Marezine, Valoid, Nausicalm

How Cyclizine is classified

Antiemetics, Antihistamines, Anti-Allergic Agents, Gastrointestinal Agents

Cyclizine During Pregnancy

Cyclizine pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Cyclizine while pregnant

N/A

Taking Cyclizine While Breastfeeding

What are recommendations for lactation if you're taking Cyclizine?

Occasional doses of cyclizine are probably acceptable during breastfeeding. Large doses or more prolonged use may cause effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established.

Maternal / infant drug levels

Occasional doses of cyclizine are probably acceptable during breastfeeding. Large doses or more prolonged use may cause effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established.

Possible effects of Cyclizine on milk supply

Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in nonlactating women and in early postpartum women.[2][3] However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment of postpartum mothers.[2] Whether lower oral doses of antihistamines have the same effect on serum prolactin or whether the effects on prolactin have any consequences on breastfeeding success have not been studied.

Possible alternatives to Cyclizine

Dimenhydrinate.