Chlorthalidone

The Basics

What is Chlorthalidone?

Used to treat high blood pressure.

Brand names for Chlorthalidone

Thalitone

How Chlorthalidone is classified

Antihypertensive Agents, Thiazide Diuretics

Chlorthalidone During Pregnancy

Chlorthalidone pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Chlorthalidone while pregnant

N/A

Taking Chlorthalidone While Breastfeeding

What are recommendations for lactation if you're taking Chlorthalidone?

Although amounts of chlorthalidone in milk are not great, its slow clearance may lead to accumulation in the infant, especially while nursing a newborn or preterm infant. It may also suppress lactation. An alternate drug may be preferred.

Maternal / infant drug levels

Although amounts of chlorthalidone in milk are not great, its slow clearance may lead to accumulation in the infant, especially while nursing a newborn or preterm infant. It may also suppress lactation. An alternate drug may be preferred.

Possible effects of Chlorthalidone on milk supply

Chlorthalidone has been used successfully to suppress lactation by giving 200 mg orally right after delivery, followed by 100 mg dailyy for 3 days in conjunction with fluid restriction and breast binding.[2] However, a comparative study found no difference between chlorthalidone 200 mg daily for 7.6 days and placebo in milk leakage and breast engorgement and pain.[3] The added contribution of the diuretic to fluid restriction and breast binding, which are effective in suppressing lactation, has not been studied. There are no data on the effects of diuretics on established, ongoing lactation.

Possible alternatives to Chlorthalidone

Chlorothiazide, Hydrochlorothiazide.