The Basics
What is Carfilzomib?
Used alone and in combination with dexamethasone or lenalidomide (Revlimid) and dexamethasone to treat people with multiple myeloma.
Brand names for Carfilzomib
Kyprolis
How Carfilzomib is classified
Antineoplastic Agents, Enzyme Inhibitors, Protein Kinase Inhibitors, Signal Transduction Inhibitors
Carfilzomib During Pregnancy
Carfilzomib pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Carfilzomib while pregnant
N/A
Taking Carfilzomib While Breastfeeding
What are recommendations for lactation if you're taking Carfilzomib?
No information is available on the clinical use of carfilzomib during breastfeeding. Because carfilzomib is 97% bound to plasma proteins, the amount in milk is likely to be low. The manufacturer recommends that breastfeeding be discontinued during carfilzomib therapy.
Maternal / infant drug levels
No information is available on the clinical use of carfilzomib during breastfeeding. Because carfilzomib is 97% bound to plasma proteins, the amount in milk is likely to be low. The manufacturer recommends that breastfeeding be discontinued during carfilzomib therapy.
Possible effects of Carfilzomib on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Carfilzomib
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
