The Basics

What is Safinamide?

Used as an add-on treatment for Parkinson’s disease during off episodes.

Brand names for Safinamide

Xadago

How Safinamide is classified

Antiparkinson Agents, Monoamine Oxidase Inhibitors

Safinamide During Pregnancy

Safinamide pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Safinamide while pregnant

N/A

Taking Safinamide While Breastfeeding

What are recommendations for lactation if you're taking Safinamide?

No information is available on the use of safinamide during breastfeeding. Because of liver toxicity in nursing rat pups, the manufacturer recommends that the drug not be used in nursing mothers. Alternate agents are preferred.

Maternal / infant drug levels

No information is available on the use of safinamide during breastfeeding. Because of liver toxicity in nursing rat pups, the manufacturer recommends that the drug not be used in nursing mothers. Alternate agents are preferred.

Possible effects of Safinamide on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Safinamide

Selegiline.

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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