The Basics
What is Asenapine?
Used to treat schizophrenia and acute mania associated with bipolar disorder.
Brand names for Asenapine
Saphris
How Asenapine is classified
Antipsychotic Agents
Asenapine During Pregnancy
Asenapine pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Asenapine while pregnant
N/A
Taking Asenapine While Breastfeeding
What are recommendations for lactation if you're taking Asenapine?
Because no information is available on the use of asenapine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Maternal / infant drug levels
Because no information is available on the use of asenapine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Possible effects of Asenapine on milk supply
Galactorrhea has been reported with asenapine.[1] Hyperprolactinemia appears to be the cause of the galactorrhea. The hyperprolactinemia is caused by the drug’s dopamine-blocking action in the tuberoinfundibular pathway. The maternal prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Possible alternatives to Asenapine
(Antipsychotic Agents) Haloperidol, Olanzapine, Risperidone.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Saphris package insert. Schering-Plough Corporation. August, 2009.
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
