The Basics

What is Echinacea / Echinacea angustifolia; Echinacea purpurea; Echinacea pallida?

Commonly used to prevent colds and other respiratory tract infections.

Brand names for Echinacea / Echinacea angustifolia; Echinacea purpurea; Echinacea pallida

Na

How Echinacea / Echinacea angustifolia; Echinacea purpurea; Echinacea pallida is classified

Complementary Therapies, Phytotherapy, Plants, Medicinal

Echinacea / Echinacea angustifolia; Echinacea purpurea; Echinacea pallida During Pregnancy

Echinacea / Echinacea angustifolia; Echinacea purpurea; Echinacea pallida pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Echinacea / Echinacea angustifolia; Echinacea purpurea; Echinacea pallida while pregnant

N/A

Taking Echinacea / Echinacea angustifolia; Echinacea purpurea; Echinacea pallida While Breastfeeding

What are recommendations for lactation if you're taking Echinacea / Echinacea angustifolia; Echinacea purpurea; Echinacea pallida?

Echinacea species (Echinacea angustifolia, Echinacea purpurea, Echinacea pallida) contain high molecular weight polysaccharides (e.g., heteroxylan, arabinogalactan) and lower molecular weight compounds (e.g., alkylamides, caffeoyl conjugates such as cichoric acid and echinacosides), but no single chemical is known to be responsible for echinacea’s biological activity. Some products have been standardized based on echinacoside, and others on cichoric acid. Echinacea has no specific uses during breastfeeding, but is commonly used orally to treat or prevent upper respiratory infections. It is also used topically to treat skin infections. Excretion of some of the purportedly active alkamides was found in breastmilk in one mother. No data exist on the safety and efficacy of echinacea in nursing mothers or infants. In general, echinacea is well tolerated with gastrointestinal upset, diarrhea and constipation, skin rash and rarely allergic reactions reported. It may also alter the metabolism of some dugs metabolized by the P450 enzyme system. Some sources indicate that echinacea is safe in recommended doses,[1] while others recommend avoiding it during breastfeeding because of the lack of published safety data. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products.

Maternal / infant drug levels

Echinacea species (Echinacea angustifolia, Echinacea purpurea, Echinacea pallida) contain high molecular weight polysaccharides (e.g., heteroxylan, arabinogalactan) and lower molecular weight compounds (e.g., alkylamides, caffeoyl conjugates such as cichoric acid and echinacosides), but no single chemical is known to be responsible for echinacea’s biological activity. Some products have been standardized based on echinacoside, and others on cichoric acid. Echinacea has no specific uses during breastfeeding, but is commonly used orally to treat or prevent upper respiratory infections. It is also used topically to treat skin infections. Excretion of some of the purportedly active alkamides was found in breastmilk in one mother. No data exist on the safety and efficacy of echinacea in nursing mothers or infants. In general, echinacea is well tolerated with gastrointestinal upset, diarrhea and constipation, skin rash and rarely allergic reactions reported. It may also alter the metabolism of some dugs metabolized by the P450 enzyme system. Some sources indicate that echinacea is safe in recommended doses,[1] while others recommend avoiding it during breastfeeding because of the lack of published safety data. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products.

Possible effects of Echinacea / Echinacea angustifolia; Echinacea purpurea; Echinacea pallida on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Echinacea / Echinacea angustifolia; Echinacea purpurea; Echinacea pallida

None listed

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Perri D, Dugoua JJ, Mills E, Koren G. Safety and efficacy of echinacea (Echinacea augustafolia, E. purpurea and E. pallida) during pregnancy and lactation. Can J Clin Pharmacol. 2006;13:e262-7. PMID: 17085774
2. Matthias A, Merika H, Addison RS et al. Bioavailability of Echinacea alkamides in human breast milk. Planta Med. 2008;74:921. Abstract. DOI: doi:10.1055/s-002-12952

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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