The Basics
What is Gadoversetamide?
An MRI contrast agent used for diagnostic procedures to provide increased enhancement and visualization of lesions of the brain, spine and liver, including tumors.
Brand names for Gadoversetamide
Optimark
How Gadoversetamide is classified
Contrast Media, Diagnostic Agents
Gadoversetamide During Pregnancy
Gadoversetamide pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Gadoversetamide while pregnant
N/A
Taking Gadoversetamide While Breastfeeding
What are recommendations for lactation if you're taking Gadoversetamide?
There is no published experience with gadoversetamide during breastfeeding. Gadoversetamide releases more free gadolinium than some other gadolinium-containing contrast agents. However, guidelines developed by several North American professional organizations state that breastfeeding need not be disrupted after a nursing mother receives a gadolinium-containing contrast medium.[1][2][3] Other agents may be preferred, especially while nursing a newborn or preterm infant.
Maternal / infant drug levels
There is no published experience with gadoversetamide during breastfeeding. Gadoversetamide releases more free gadolinium than some other gadolinium-containing contrast agents. However, guidelines developed by several North American professional organizations state that breastfeeding need not be disrupted after a nursing mother receives a gadolinium-containing contrast medium.[1][2][3] Other agents may be preferred, especially while nursing a newborn or preterm infant.
Possible effects of Gadoversetamide on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Gadoversetamide
Gadobenate, Gadobutrol, Gadopentetate, Gadoteridol, Gadoterate.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. American College of Radiology Committee on Drugs and Contrast Media. Administration of contrast media to breast-feeding mothers. In, ACR manual on contrast media. 2017;Version 10.3:102-3. https://www.acr.org/~/media/37D84428BF1D4E1B9A3A2918DA9E27A3.pdf
2. Patenaude Y, Pugash D, Lim K et al. The use of magnetic resonance imaging in the obstetric patient. J Obstet Gynaecol Can. 2014;36:349-55. PMID: 24798674
3. Committee Opinion No. 723: Guidelines for Diagnostic Imaging During Pregnancy and Lactation. Obstet Gynecol. 2017;130:e210-e216. PMID: 28937575
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
