The Basics
What is Gadofosveset?
Used in combination with magnetic resonance angiography (MRA) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRA.
Brand names for Gadofosveset
Vasovist, Ablavar
How Gadofosveset is classified
Contrast Media, Diagnostic Agents
Gadofosveset During Pregnancy
Gadofosveset pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Gadofosveset while pregnant
N/A
Taking Gadofosveset While Breastfeeding
What are recommendations for lactation if you're taking Gadofosveset?
There is no published experience with gadofosveset during breastfeeding. Guidelines developed by several North American professional organizations state that breastfeeding need not be disrupted after a nursing mother receives a gadolinium-containing contrast medium.[1][2][3] However, because there is no published experience with gadofosveset during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
Maternal / infant drug levels
There is no published experience with gadofosveset during breastfeeding. Guidelines developed by several North American professional organizations state that breastfeeding need not be disrupted after a nursing mother receives a gadolinium-containing contrast medium.[1][2][3] However, because there is no published experience with gadofosveset during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
Possible effects of Gadofosveset on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Gadofosveset
Gadobenate, Gadobutrol, Gadopentetate, Gadoteridol, Gadoterate.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. American College of Radiology Committee on Drugs and Contrast Media. Administration of contrast media to breast-feeding mothers. In, ACR manual on contrast media. 2017;Version 10.3:102-3. https://www.acr.org/~/media/37D84428BF1D4E1B9A3A2918DA9E27A3.pdf
2. Patenaude Y, Pugash D, Lim K et al. The use of magnetic resonance imaging in the obstetric patient. J Obstet Gynaecol Can. 2014;36:349-55. PMID: 24798674
3. Committee Opinion No. 723: Guidelines for Diagnostic Imaging During Pregnancy and Lactation. Obstet Gynecol. 2017;130:e210-e216. PMID: 28937575
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
