Dapagliflozin

The Basics

What is Dapagliflozin?

helps treat type 2 diabetes

Brand names for Dapagliflozin

Farxiga

How Dapagliflozin is classified

Hypoglycemic Agents, Sodium-Glucose Cotransporter 2 Inhibitors, SGLT2 Inhibitors

Dapagliflozin During Pregnancy

Dapagliflozin pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Dapagliflozin while pregnant

N/A

Taking Dapagliflozin While Breastfeeding

What are recommendations for lactation if you're taking Dapagliflozin?

No information is available on the clinical use of dapagliflozin during breastfeeding. Dapagliflozin is an uncharged molecule that is 91% protein bound in plasma, so it is unlikely to pass into breastmilk in clinically important amounts. The manufacturer does not recommend dapagliflozin during breastfeeding because of a theoretical risk to the infant’s developing kidney. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Maternal / infant drug levels

No information is available on the clinical use of dapagliflozin during breastfeeding. Dapagliflozin is an uncharged molecule that is 91% protein bound in plasma, so it is unlikely to pass into breastmilk in clinically important amounts. The manufacturer does not recommend dapagliflozin during breastfeeding because of a theoretical risk to the infant’s developing kidney. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Possible effects of Dapagliflozin on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Dapagliflozin

Acarbose, Glipizide, Glyburide, Insulin, Metformin, Miglitol.