The Basics
What is Mangafodipir?
A contrast agent used as a diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver and pancreas.
Brand names for Mangafodipir
Teslascan
How Mangafodipir is classified
Contrast Media, Diagnostic Agents
Mangafodipir During Pregnancy
Mangafodipir pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Mangafodipir while pregnant
The safety of TESLASCAN (mangafodipir) in human pregnancy has not been established. TESLASCAN (mangafodipir) must not be used during pregnancy (see the CONTRAINDICATIONS section). Prior to administration of TESLASCAN (mangafodipir) to women of child bearing potential, pregnancy should be excluded. Pre-clinical studies in rats have established teratogenic effects when TESLASCAN (mangafodipir) was given repeatedly during major organogenesis. TESLASCAN (mangafodipir) causes foetotoxicity and embryotoxicity in rabbits. TESLASCAN (mangafodipir) is not teratogenic in rabbits. TESLASCAN (mangafodipir) has no effect on male or female fertility in rats.
Taking Mangafodipir While Breastfeeding
What are recommendations for lactation if you're taking Mangafodipir?
Mangafodipir is a chelate of manganese that releases free manganese ions into the bloodstream after it is metabolized. Because there is no published experience with mangafodipir during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
Maternal / infant drug levels
Mangafodipir is a chelate of manganese that releases free manganese ions into the bloodstream after it is metabolized. Because there is no published experience with mangafodipir during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
Possible effects of Mangafodipir on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Mangafodipir
Ferumoxides, Gadopentetate.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
