The Basics
What is Bendroflumethiazide?
A diuretic used to treat high blood pressure (hypertension) and the build-up of fluid in your body
Brand names for Bendroflumethiazide
Corzide
How Bendroflumethiazide is classified
Antihypertensive Agents, Thiazide Diuretics
Bendroflumethiazide During Pregnancy
Bendroflumethiazide pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Bendroflumethiazide while pregnant
Thiazides cross the placental barrier and appear in cord blood. The use of thiazides in pregnant women requires that the anticipated benefit be weighed against possible hazards to the fetus. These hazards include fetal or neonatal jaundice, thrombocytopenia, and possibly other adverse reactions which have occurred in the adult.
Taking Bendroflumethiazide While Breastfeeding
What are recommendations for lactation if you're taking Bendroflumethiazide?
No information is available on the amount of bendroflumethiazide in breastmilk. Intense diuresis with large doses of bendroflumethiazide can decrease breastmilk production, especially during the neonatal period. Shorter-acting diuretics in low doses are preferred over bendroflumethiazide.
Maternal / infant drug levels
No information is available on the amount of bendroflumethiazide in breastmilk. Intense diuresis with large doses of bendroflumethiazide can decrease breastmilk production, especially during the neonatal period. Shorter-acting diuretics in low doses are preferred over bendroflumethiazide.
Possible effects of Bendroflumethiazide on milk supply
Bendroflumethiazide has been used to suppress lactation in oral doses of 5 mg twice daily for 5 days,[1] and in doses of 10 mg in the morning and 5 mg in the afternoon.[2] The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of potent diuretics on established, ongoing lactation.
Possible alternatives to Bendroflumethiazide
Chlorothiazide, Hydrochlorothiazide.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Healy M. Suppressing lactation with oral diuretics. Lancet. 61;1:1353-4.
2. Stout G. Suppression of lactation. Br Med J. 62;1:1150. Letter. PMC: PMC1958377
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
