Lisinopril

The Basics

What is Lisinopril?

Used to treat high blood pressure.

Brand names for Lisinopril

Zestril

How Lisinopril is classified

Antihypertensive Agents, Angiotensin-Converting Enzyme Inhibitors, ACE Inhibitors, ACEIs

Lisinopril During Pregnancy

Lisinopril pregnancy category

Category C/D/D

Note that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Lisinopril while pregnant

Zestril can cause fetal harm when administered to a pregnant woman. Use of drugs that act on the reninangiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Most epidemiologic studies examining fetal abnormalities after exposure to antihypertensive use in the first trimester have not distinguished drugs affecting the renin-angiotensin system from other antihypertensive agents. When pregnancy is detected, discontinue Zestril as soon as possible. The estimated background risk of major birth defects and miscarriage for the indicated population(s) are unknown. In the general U.S. population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2-4% and 15-20%, respectively.

Taking Lisinopril While Breastfeeding

What are recommendations for lactation if you're taking Lisinopril?

Because no information is available on the use of lisinopril during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Maternal / infant drug levels

Because no information is available on the use of lisinopril during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Possible effects of Lisinopril on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Lisinopril

Benazepril, Captopril, Enalapril, Quinapril.