The Basics On Ceteareth-25

What is Ceteareth-25?

A fatty alcohol that functions as an emulsifier and surfactant in cosmetics.

What are other names for Ceteareth-25?

CETEARETH-25, PEG-25 CETYL/STEARYL ETHER, POLYETHYLENE GLYCOL (25) CETYL/STEARYL ETHER, and POLYOXYETHYLENE (25) CETYL/STEARYL ETHER

What is Ceteareth-25 used for?

Ceteareth-25 is non-ionic polyoxyethylene ether of higher saturated fatty alcohols (cetyl/stearyl alcohol). It forms a colloid solution in water and alcohol. It is an universal emulsifier to make o/w emulsions. Widely used in creams and lotions, foundation and sunscreens.

How Ceteareth-25 is classified

Emulsifiers, Texture Enhancer

Recommendations for using Ceteareth-25 during pregnancy and breastfeeding

Limited data suggests no known risk

 

Ceteareth-25 During Pregnancy

What we know about using Ceteareth-25 while pregnant or breastfeeding

Limited information available.

A 2-generation reproductive study was performed using Fischer 344 rats to examine whether C9-I I pareth 6 had any effect on reproductive parameters.44 The Fo groups, consisting of 30 males and 30 females, were exposed dermally to I rnL/kg of 0%, 1%, 10%, or 25% w/v aqueous C9-l I pareth 6 for 119 days prior to mating. The test site was shaved, but the application sites were not covered. The test material was not applied during mating to avoid ingestion. For the second generation, after 133 days of dosing, groups of 20 males and 20 females per test group were mated. For both generations, the application sites were evaluated for irritation. The male rats of both generations were killed following mating. Gross necropsies were performed on all Fo and Fl parents and on 5 pups/ gender per dose. There was no mortality in the Fo generations, and deaths that did occur in the Fl generation were not attributed to treatment. No irritation was observed for any of the animals, but dry flaking skin was observed in the 10% and 25% dose groups. For effects on body weight, 10% was a no-effect level and 25% C9-11 pareth 6 caused a minimal decrease in body weights over the study. There were no compound-related effects on matemal body weights in any test group. No toxicologically significant

General safety info about Ceteareth-25 from CIR

The CIR Expert Panel assessed the safety of Alkyl PEG Ethers as used in cosmetics. These ingredients primarily function in cosmetics as surfactants, and some have additional functions as skin-conditioning agents, fragrance ingredients, and emulsion stabilizers. The Panel reviewed available relevant animal and clinical data, as well as information from previous CIR reports; when data were not available for individual ingredients, the Panel extrapolated from the existing data to support safety. The Panel concluded that the Alkyl PEG ethers are safe as used when formulated to be nonirritating, and the same applies to future alkyl PEG ether cosmetic ingredients that vary from those ingredients recited herein only by the number of ethylene glycol.

Use this, not that!

Products where you might find Ceteareth-25

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List of References

General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/

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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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