The Basics On Pantothenic Acid
What is Pantothenic Acid?
Also called vitamin B5, and often touted for a variety of benefits to skin.
What are other names for Pantothenic Acid?
PANTOTHENIC ACID/YEAST POLYPEPTIDE
What is Pantothenic Acid used for?
Pantothenic acid (or Vitamin B5), offers excellent anti-inflammatory, moisturizing, restorative and wound healing benefits for our skin. It is highly unstable and is usually present in formulations as the alcohol derivative known as Panthenol (also known as Dexpanthenol or Provitamin B5).
How Pantothenic Acid is classified
Vitamins
Recommendations for using Pantothenic Acid during pregnancy and breastfeeding
Limited data suggests no known risk
Pantothenic Acid During Pregnancy
What we know about using Pantothenic Acid while pregnant or breastfeeding
Limited information available.
Two different groups of female albino rats were supplemented with the same vitamin mixture and either 100 µg or 1 mg Calcium Pantothenate after giving birth to their first litter (stock diet for all female rats during first pregnancies) and through the birth of young from their second pregnancies (gestation period not provided).4 The young born from both the first and second pregnancies were normal. No teratogenicity or fetotoxicity were reported. Provided below is a summary of DART studies that are presented in detail in Table 9. DL-Panthenyl Ethyl Ether (up to 1000 mg/kg/day) was administered by gavage to pregnant rats 1x/day on days 6 through 19 of gestation using GLP and in accordance with OECD TG 421; the maternal and developmental NOAELs were reported to be ≥ 1000 mg/kg/day. 6 In different experiments examining the effects of orally administered Calcium Pantothenate (up to 2000 mg/kg) on pregnant rats (details on gestation were not provided) no toxicity, teratogenicity, or fetotoxicity was reported; Calcium Pantothenate was found to cross the placenta.12
General safety info about Pantothenic Acid from CIR
The Cosmetic Ingredient Review (CIR) Expert Panel assessed the safety of Panthenol, Pantothenic Acid, and 5 derivatives as used in cosmetics. These ingredients named in this report are reported to function in cosmetics as hair conditioning agents, and Panthenol also is reported to function as a skin-conditioning agent-humectant and a solvent. The Panel reviewed relevant data for these ingredients, and concluded that these 7 ingredients are safe in cosmetics in the present practices of use concentration described in this safety assessment.
Use this, not that!
Products where you might find Pantothenic Acid
Sunday Riley GOOD GENES Glycolic Acid Treatment;Sunday Riley GOOD GENES All-In-One Lactic Acid Treatment ;Paula’s Choice 10% Azelaic Acid Booster;Lancer Skincare The Method: Body Nourish with Hylaplex and Glycolic Acid 10%;Paula’s Choice RESIST Daily Smoothing Treatment with 5% Alpha Hydroxy Acid; 8Greens 8Greens Gummies Dietary Supplement
List of References
General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
