The Basics On Palmitoyl Proline
What is Palmitoyl Proline?
Palmitoyl proline combines fatty acid palmitic acid with the amino acid proline.
What are other names for Palmitoyl Proline?
N-PALMITOYL-L-PROLINE SODIUM SALT, SODIUM 5-OXO-1-PALMITOYL-L-PROLINATE, and SODIUM PALMITOYL PROLINE
What is Palmitoyl Proline used for?
On skin, palmitoyl proline acts as a surface treatment by contributing a soft feeling. It also helps cosmetic pigments stay blended in a formula. The proline component can help shore up skin’s natural supportive elements while the palmitic acid portion prevents moisture loss.
How Palmitoyl Proline is classified
Skin-Softening, Hydration
Recommendations for using Palmitoyl Proline during pregnancy and breastfeeding
Limited data suggests no known risk
Palmitoyl Proline During Pregnancy
What we know about using Palmitoyl Proline while pregnant or breastfeeding
Limited information available.
In teratology studies, no evidence of impaired fertility or toxicity to fetuses was observed in rats at oral doses up to 2,000 mg/ kg/d acetyl cysteine and in rabbits at oral doses up to 1,000 mg/ kg/d acetyl cysteine.33 No further details were provided. Male rats treated orally with 250 mg/kg/d acetyl cysteine for 15 weeks did not experience adverse effects to fertility or reproductive performance.33 No further details were provided.
General safety info about Palmitoyl Proline from CIR
The Cosmetic Ingredient Review Expert Panel reviewed the product use, formulation, and safety data of 115 amino acid alkyl amides, which function as skin and hair conditioning agents and as surfactants—cleansing agents in personal care products. Safety test data on dermal irritation and sensitization for the ingredients with the highest use concentrations, lauroyl lysine and sodium lauroyl glutamate, were reviewed and determined to adequately support the safe use of the ingredients in this report. The Panel concluded that amino acid alkyl amides are safe in the present practices of use and concentration in cosmetics, when formulated to be nonirritating.
Use this, not that!
Products where you might find Palmitoyl Proline
Grande Cosmetics GrandeLASH-MD Lash Enhancing Serum Mini; Grande Cosmetics GrandeBROW Brow Enhancing Serum Mini; Dr. Lara Devgan Scientific Beauty Platinum Lip Plump SPF 30
List of References
General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
