Methyl Glucose Sesquistearate

The Basics On Methyl Glucose Sesquistearate

What is Methyl Glucose Sesquistearate?

A mixure of the diesters of methyl glucoside and stearic acid.

What are other names for Methyl Glucose Sesquistearate?

D-GLUCOPYRANOSIDE, METHYL, OCTADECANOATE, DGLUCOPYRANOSIDE, METHYL, OCTADECANOATE (2:3), METHYL GLUCOSE SESQUISTEARATE, METHYL GLUCOSIDE SESQUISTEARATE, METHYL OCTADECANOATE D-GLUCOPYRANOSIDE, and OCTADECANOATE D-GLUCOPYRANOSIDE, METHYL

What is Methyl Glucose Sesquistearate used for?

How Methyl Glucose Sesquistearate is classified

Emollients, Skin-Softening

Recommendations for using Methyl Glucose Sesquistearate during pregnancy and breastfeeding

Limited data suggests no known risk

 

Methyl Glucose Sesquistearate During Pregnancy

What we know about using Methyl Glucose Sesquistearate while pregnant or breastfeeding

Limited information available.

Isostearic Acid, Esters with Methyl α-D-Glucoside A combined repeated dose toxicity study with a reproduction/developmental toxicity screening test was performed according to the OECD 422 test protocol.35 Isostearic acid, esters with methyl α-D-glucoside (in1% aqueous carboxymethyl cellulose) was administered orally (gavage) to the following dose groups (10 male and 10 female Han rats/dose group) daily: 50, 150, and 1000 mg/kg body weight per day. The fourth group served as the negative control. The males were dosed for 2 weeks prior to mating, during mating, and up to termination (30 days total). Females were dosed for 2 weeks prior to mating, during mating, during post-coitum, and for at least 4 days of lactation (42 to 44 days total). Ten litters per dose group were delivered. There were also no treatment-related changes in reproduction, breeding, or pup development. The reproduction, 13 breeding, and developmental NOAEL was defined as ≥ 1000 mg/kg/day. Results relating to repeated dose toxicity in adult rats are included in that section of the report.

General safety info about Methyl Glucose Sesquistearate from CIR

Methyl glucose polyethers and esters function as skin/hair conditioning agents, surfactants, and viscosity increasing agents. The ester ingredients in this report are mono-, di-, or tri-carboxyester substituted methyl glucosides, and the polyether ingredients in this report are mixtures of various chain-lengths. After reviewing the data, including the molecular weights, log Kows, and other properties of these ingredients, the Panel determined that there likely would be no significant skin penetration of these ingredients. Although there are data gaps in this report, the Panel concluded that similarities between molecular structures, physicochemical and biological characteristics, and functions and concentrations in cosmetics allowed grouping these ingredients together and extending the available toxicological data to support the safety of each of the ingredients in the group. The Expert Panel concluded that the methyl glucose polyethers and esters are safe in the present practices of use and concentration.

Use this, not that!

Products where you might find Methyl Glucose Sesquistearate

Kerastase Nutritive Conditioner for Normal to Dry Hair; Kerastase Nutritive Shampoo for Normal to Dry Hair; Kerastase Nutritive Mask for Dry Fine Hair