The Basics On Calcium Ascorbate
What is Calcium Ascorbate?
Form of vitamin C.
What are other names for Calcium Ascorbate?
CALCIUM ASCORBATE, CALCIUM DIASCORBATE, CALCIUM SALT (2:1) DIHYDRATE L-ASCORBIC ACID, DIHYDRATE L-ASCORBIC ACID, CALCIUM SALT (2:1), L-ASCORBIC ACID, CALCIUM SALT (2:1), DIHYDRATE, and LASCORBIC ACID, CALCIUM SALT (2:1)
What is Calcium Ascorbate used for?
Vitamin C is the predominant and most common innate anti-oxidant agent for our skin5. It plays a vital role in healing wounds and photodamaged skin6. As well as itself being a powerful antioxidant, Vitamin C has been shown to regenerate and enhance the effects of skin other antioxidants, including alpha-tocopherol (vitamin E)5. The combination of Vitamin C (at 15%) and Vitamin E (at 1%) added topically exhibited a greater protection against sunburn, photoaging and skin cancer7. Vitamin C applied topically over a three month period has been shown to repair photodamaged skin and protect the skin from UV induced photodamage3. Incorporation of Ferulic acid into a topical solution of 15% l-ascorbic acid and 1% alpha-tocopherol improved the chemical stability of both vitamins (C+E) and doubled photoprotection to solar-simulated irradiation of skin from 4-fold to approximately 8-fold as measured by both erythema and sunburn cell formation8.
How Calcium Ascorbate is classified
Antioxidants, Vitamins
Recommendations for using Calcium Ascorbate during pregnancy and breastfeeding
Limited data suggests no known risk
Calcium Ascorbate During Pregnancy
What we know about using Calcium Ascorbate while pregnant or breastfeeding
Limited information available.
Computational Analyses/Predictions Ascorbyl Palmitate Using an in silico methodology (described at beginning of Toxicological Studies section), Ascorbyl Palmitate was predicted not to be a reproductive toxicant.41 Ascorbyl Stearate Using an in silico methodology (described at beginning of Toxicological Studies section), Ascorbyl Stearate was predicted not to be a reproductive toxicant.
General safety info about Calcium Ascorbate from CIR
No report found.
Use this, not that!
Products where you might find Calcium Ascorbate
Youth To The People Superberry Hydrate + Glow Dream Mask with Vitamin C, Beautycounter Counter+ All Bright C Serum, Biossance Squalane + Vitamin C Rose Oil
List of References
General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
1. Al-Niaimi F, Chiang N. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. J Clin Aesthet Dermatol. 2017;10(7):14-17. [PubMed] 2. Hinek A, Kim H, Wang Y, Wang A, Mitts T. Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin. J Dermatol Sci. 2014;75(3):173-182. [PubMed] 3. Traikovich S. Use of topical ascorbic acid and its effects on photodamaged skin topography. Arch Otolaryngol Head Neck Surg. 1999;125(10):1091-1098. [PubMed] 4. Pinnell S, Yang H, Omar M, et al. Topical L-ascorbic acid: percutaneous absorption studies. Dermatol Surg. 2001;27(2):137-142. [PubMed] 5. Chen L, Hu J, Wang S. The role of antioxidants in photoprotection: a critical review. J Am Acad Dermatol. 2012;67(5):1013-1024. [PubMed] 6. Moores J. Vitamin C: a wound healing perspective. Br J Community Nurs. 2013;Suppl:S6, S8-11. [PubMed] 7. Lin J, Selim M, Shea C, et al. UV photoprotection by combination topical antioxidants vitamin C and vitamin E. J Am Acad Dermatol. 2003;48(6):866-874. [PubMed] 8. Lin F, Lin J, Gupta R, et al. Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. J Invest Dermatol. 2005;125(4):826-832. [PubMed] 9. Gönüllü U, Yener G, Uner M, Incegül T. Moisturizing potentials of ascorbyl palmitate and calcium ascorbate in various topical formulations. Int J Cosmet Sci. 2004;26(1):31-36. [PubMed] 10. Uchida Y, Behne M, Quiec D, Elias P, Holleran W. Vitamin C stimulates sphingolipid production and markers of barrier formation in submerged human keratinocyte cultures. J Invest Dermatol. 2001;117(5):1307-1313. [PubMed] 11. Kim K, Shin K, Park K, et al. Vitamin C Stimulates Epidermal Ceramide Production by Regulating Its Metabolic Enzymes. Biomol Ther (Seoul). 2015;23(6):525-530. [PubMed] 12. Shimada Y, Tai H, Tanaka A, et al. Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo. J Periodontol. 2009;80(2):317-323. [PubMed] 13. Panich U, Tangsupa-a-nan V, Onkoksoong T, et al. Inhibition of UVA-mediated melanogenesis by ascorbic acid through modulation of antioxidant defense and nitric oxide system. Arch Pharm Res. 2011;34(5):811-820. [PubMed] 14. Kishimoto Y, Saito N, Kurita K, Shimokado K, Maruyama N, Ishigami A. Ascorbic acid enhances the expression of type 1 and type 4 collagen and SVCT2 in cultured human skin fibroblasts. Biochem Biophys Res Commun. 2013;430(2):579-584. [PubMed] 15. Humbert P, Haftek M, Creidi P, et al. Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo. Exp Dermatol. 2003;12(3):237-244. [PubMed] 16. Herndon J, Jiang L, Kononov T, Fox T. An Open Label Clinical Trial to Evaluate the Efficacy and Tolerance of a Retinol and Vitamin C Facial Regimen in Women With Mild-to-Moderate Hyperpigmentation and Photodamaged Facial Skin. J Drugs Dermatol. 2016;15(4):476-482. [PubMed] 17. Burgess C. Topical vitamins. J Drugs Dermatol. 2008;7(7 Suppl):s2-6. [PubMed] 18. Elmore A. Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics. Int J Toxicol. 2005;24 Suppl 2:51-111. [PubMed] 19. Wang K, Jiang H, Li W, Qiang M, Dong T, Li H. Role of Vitamin C in Skin Diseases. Front Physiol. 2018;9:819. [PubMed] 20. Gallarate M, Carlotti M, Trotta M, Bovo S. On the stability of ascorbic acid in emulsified systems for topical and cosmetic use. Int J Pharm. 1999;188(2):233-241. [PubMed]
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
