Biotin

The Basics On Biotin

What is Biotin?

A water-soluble vitamin that’s a part of the vitamin B family and also known as vitamin H.

What are other names for Biotin?

1H-THIENO[3,4-D]IMIDAZOLE-4-PENTANOIC ACID, HEXAHYDRO-2-OXO-, (3AS,4S,6AR)-, 1H-THIENO[3,4-D]IMIDAZOLE-4-PENTANOIC ACID, HEXAHYDRO-2-OXO-, [3AS-(3AA ,4B,6AA)]-, 1HTHIENO[3,4D]IMIDAZOLE4PENTANOIC ACID, HEXAHYDRO2OXO, [3AS(3AÃ ,4 ,6AÃ )], BIOTIN, COENZYME R, HEXAHYDRO-2-OXO- [3AS-(3AA ,4B,6AA)]- 1H-THIENO[3,4-D]IMIDAZOLE-4-PENTANOIC ACID, VITAMIN B7, VITAMIN H, [3AS-(3AA ,4B,6AA )]-HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOLE-4-PENTANOIC ACID, and [3AS-(3AA ,4B,6AA)]- 1H-THIENO[3,4-D]IMIDAZOLE-4-PENTANOIC ACID, HEXAHYDRO-2-OXO-

What is Biotin used for?

Biotin is a water-soluble vitamin that’s a part of the vitamin B family. It’s also known as vitamin H. Your body needs biotin to help convert certain nutrients into energy. It also plays an important role in the health of your hair, skin, and nails. If you aren’t getting enough biotin, you may experience hair loss or a scaly red rash. However, a deficiency is rare. In most cases, the biotin you get from your diet is enough for you to reap the health benefits it offers.

How Biotin is classified

Vitamins

Recommendations for using Biotin during pregnancy and breastfeeding

Is biotin safe during pregnancy? Limited data on taking biotin while pregnant or breastfeeding suggests no known risk

 

Biotin During Pregnancy

What we know about using Biotin while pregnant or breastfeeding

Can you take biotin while pregnant? Limited information about taking biotin while pregnant is available.

In a number of reproductive studies using rats, the number of resorptions in animals dosed with Biotin by subcutaneous (s.c.) injection was increased as compared to controls, and fetal, uterine, and placental weights were decreased.1 Dosing with estrogen generally prevented the resorptions. In a reproductive study in which mice were dosed with Biotin orally and by s.c. injection, significant differences were not observed between treated and control groups. Groups of male Wistar rats were fed a control diet (containing 0.00004% Biotin; n=5) or a diet supplemented with 0.01% (n=6), 0.1% (n=6), or 1.0% Biotin (n=12), and a pair-fed group (n=12) was given control diet equal in calories to that ingested by the 1.0% Biotin group.19 Half of the animals in the 1.0% Biotin and the pair-fed group were fed for 8 wks, and the other animals were given their respective diets for 6 wks. All animals were killed at the termination of dosing (i.e., at 56 or 42 days, respectively). There were no differences in feed consumption or body weights in the low or mid-dose group when compared to controls, but growth in the high-dose group was less than in controls. Hair loss and mucosal erosion were observed in the high dose animals after 4 wks of dosing, and one high-dose animal died within the 6 wk feeding period. Liver and spleen weights were statistically significantly decreased in the 0.01% (but not the 0.1%) group when compared to controls, and kidney, brain, and testis weights were statistically significantly decreased in the 1.0% group as compared to the pair-fed group. Most hematology parameters did not change, but total cholesterol, total protein, and albumin were statistically significantly decreased in the 1.0% group compared to the pair-fed group. Administration of 1% Biotin in the diet resulted in a decreased sperm count; the sperm count in the caudal epididymis of rats of the pair-fed group was 34 ± 25 x 106 /ml, and it was <1 sperm/ml in rats of the 1% Biotin group. There was a statistically significant increase in the number of sperm with an abnormal (mostly round) head in the 1% group, and only a few spermatogonia and no spermatocytes were present in this group. The diameters of the seminiferous tubules were statistically significantly lower in the 1.0% Biotin group, as compared to the pair-fed group (230.0 ± 24.5 µm vs. 342.5 ± 26.3 µm). Apoptosis was not observed, and there were no significant differences in testosterone levels in the testes among the groups. (No results for these parameters were presented for the low and mid-dose groups.) The effect of Biotin-supplementation on the mouse female reproductive system was evaluated by feeding BALB/cAnN Hsd mice a diet supplemented with 410 µmol/kg diet for 9 wks.20 A statistically significant increase in serum estradiol concentrations (73 ± 6.0 vs. 35 ± 2.2 pmol/l in controls) and in CYP1A2 activity (40 ± 7.1 vs. 32 ± 4.6 pmol/mg/protein/min in controls) was observed. Primary and Graafian follicles were decreased approximately 50% compared to controls. There were no significant changes in in the estrous cycle, progesterone concentrations, or in the number of corpora lutea in the ovary

General safety info about Biotin from CIR

No report found.

Use this, not that!

Products where you might find Biotin

R+Co DALLAS Biotin Thickening Shampoo (8.5 fl. oz.); Supermood Radiance Capsules (75 count); Briogeo B. Well Vegan Omega 3,6,9 + Biotin Supplements (60 tablets); R+Co DALLAS Biotin Thickening Conditioner (8.5 fl. oz.); R+Co DALLAS Biotin Thickening Shampoo (33.8 fl. oz.); Briogeo B. Well Vegan Omegas + Biotin Supplements for Hair Thinning; Briogeo Blossom & Bloom Ginseng + Biotin Hair Volumizing Shampoo; Briogeo Blossom & Bloom Ginseng + Biotin Hair Volumizing Shampoo; Briogeo Blossom & Bloom Ginseng + Biotin Hair Volumizing Shampoo; Briogeo Blossom & Bloom Ginseng + Biotin Hair Volumizing Shampoo