The Basics On Zinc Gluconate

What is Zinc Gluconate?

Zinc gluconate is the zinc salt of gluconic acid produced from glucose that functions as a preservative.

What are other names for Zinc Gluconate?

BIS(D-GLUCONATO-1,2 ) ZINC, BIS(D-GLUCONATO-1,2- ZINC, BIS(D-GLUCONATO-O1,O2)ZINC, ZINC GLUCONATE, ZINC, BIS(D-GLUCONATO-.KAPPA.O1,.KAPPA.O2)-, (T-4)-, ZINC, BIS(D-GLUCONATO-1,2-, and ZINC, BIS(DGLUCONATOO1,O2)

What is Zinc Gluconate used for?

Namely Zinc Gluconate is used in cosmetics for its antiseptic and astringent properties. It is often used in acne treatment products, it accelerates the healing of wounds and helps the body to transform essential fatty acids used by the skin for healing. It is also found in deodorants and toothpastes.

How Zinc Gluconate is classified

Preservatives, Hydration

Recommendations for using Zinc Gluconate during pregnancy and breastfeeding

Limited data suggests no known risk

 

Zinc Gluconate During Pregnancy

What we know about using Zinc Gluconate while pregnant or breastfeeding

Limited information available.

Mice were given 500 or 1000 mg/l Zinc Acetate in the drinking water from mating through weaning; a lowest-observable-adverseeffect-level (LOAEL) of 136 mg/kg/day zinc in male and female mice was reported due to an increase in direct plaque-forming activity of spleen cells and an increase in lymphocyte proliferation with mitogen stimulation. 13 In rats dosed by gavage with up to 30 mg/kg/day aq. Zinc Chloride for 84 days (premating through lactation), adverse effects were reported in the dams and the offspring, including a reduced number of live pups/litter, a decreased live birth index, increased mortality, and increased fetal resorption. 83 In a two-generation reproduction toxicity study in which rats were dosed with up to 30 mg/kg/day aq. Zinc Chloride, the overall no-observed-adverse-effect-level (NOAEL) was 7.5 mg/kg/day for the F1 generation.14,84 Parental animals from F0 and F1 generations showed reduced fertility and viability, and effects on organ weights were reported in parental animals; reduced body weights were reported for F1 and F2 pups in 30 mg/kg/day group, however no effects on weaning index, sex ratio, or litter size observed. The developmental and reproductive effects of Zinc Sulfate was examined in mice (‚â§ 30 mg/kg/day), 10 rats (up to 42.5 mg/kg) 85, hamsters (‚â§ 88 mg/kg/day), 9,20 and rabbits (‚â§ 60 mg/kg);85 no developmental effects were observed. In studies in which male rats were fed a diet containing 4000 ppm zinc as Zinc Sulfate, 10,86 there was a decrease in the conception rate, and a statistically significantly lower number of live births per mated female. In a study in which female rats were fed a diet containing 4000 ppm zinc as Zinc Sulfate, a decrease in the conception rate was reported when the animals were dosed from the first day of conception through study termination, but not in the group that were dosed 21-26 days prior to dosing, through day 18 of gestation; there were no other statistically significant effects on reproductive parameters.87

General safety info about Zinc Gluconate from CIR

No report found.

Use this, not that!

Products where you might find Zinc Gluconate

Kerastase Reflection Mask for Color-Treated Hair; Dior Capture Youth Matte Maximizer Age-Delay Mattifying Serum; Dior Diorsnow Illuminating Cloud Cream

 

 

 

List of References

General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/

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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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