Polysorbates

The Basics On Polysorbates

What is Polysorbates?

Large group of ingredients most often derived from lauric acid, which is derived from coconuts.

What are other names for Polysorbates?

POLYSORBATE

What is Polysorbates used for?

Polysorbates are used in a variety of skincare, haircare, makeup and cleaning products. They alter surface tension and their inclusion in formulations is usually to help dissolve oils into water.

How Polysorbates is classified

Cleansing Agents

Recommendations for using Polysorbates during pregnancy and breastfeeding

Limited data suggests no known risk

 

Polysorbates During Pregnancy

What we know about using Polysorbates while pregnant or breastfeeding

Limited information available.

PEGs Sorbitan Beeswax Data on the reproductive or developmental toxicity of the PEGs Sorbitan Beeswax ingredients were not found. Data on PEGs and Sorbitol are provided. Because of concerns about the reproductive and developmental toxicity of the PEG monomer, ethylene glycol, a separate section is included to address that issue. PEGs No adverse reproductive effects occurred during subchronic (90 days) and chronic (2 years) oral toxicity studies ofPEG-6-32 and PEG-75. In the subchronic study, PEG-75 was tested at a dose of 0.23 g/kg/day. In the chronic study, PEG-75 was tested at doses up to 0.062 g/kg/day and, PEG-6-32, at doses up to 1.69 g/kg/day (Andersen 1993). Sorbitol MacKenzie eta!. ( 1986) performed a multigeneration feeding study to determine the reproductive and developmental effects of Sorbitol. Twelve male and 24 female Charles River CD (SD) BR rats per group were fed diets having 2.5%, 5.0%, or 10% Sorbitol (replacing the sucrose content of the basal feed) during a 96-week multigeneration study. The two high concentrations were “built up in 2.5% steps at weekly intervals.” The F0 rats were mated to produce the F1a and F1b litters. The F1b rats were treated and mated to produce the F2a and F2b litters. The F2b rats were treated and mated to produce the F3a litters. Twelve rats/sex/group were fed the test diets for 4 weeks, then were killed. Gross examinations were performed on all mated animals and two rats/sex of the F1a and F2 ‚Ä¢. Gross and microscopic examinations and biochemical analyses were performed on the F3a rats. In this study, the feeding of up to 10% Sorbitol to rats had no significant adverse clinical, behavioral, or reproductive effects. and no significant gross or microscopic changes were observed. The safety of hydrogenated starch hydrolysates (HSH), which are mixtures of polyhydric alcohols such as ~7.0% Sorbitol. was investigated using a 2-year ingestion study (50 SpragueDawley rats/sex/group), a multigeneration reproduction study (20 rats/sex/group), and a teratology study (30 dams/group). At a concentration of 18% in drinking water (3000 to 7000 mg/ kg/day), HSH did not produce reproductive or developmentai effects (Modderman 1993).

General safety info about Polysorbates from CIR

No report found.

Use this, not that!

Products where you might find Polysorbates

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