Papaya Extract

The Basics On Papaya Extract

What is Papaya Extract?

Extract that is the source of papain.

What are other names for Papaya Extract?

CARICA PAPAYA (PAPAYA) FRUIT EXTRACT, CARICA PAPAYA EXTRACT, CARICA PAPAYA FRUIT EXTRACT, EXTRACT OF CARICA PAPAYA, EXTRACT OF PAPAYA FRUIT, PAPAYA EXTRACT, and PAPAYA FRUIT EXTRACT

What is Papaya Extract used for?

Papaya fruit extract makes an effective, nonabrasive exfoliant. An enzyme in the fruit, papain, helps to remove impurities and slough away dead skin cells. Regular use of the ingredient is said to help to fade acne spots, scars, and sun damage. … Papaya fruit extract is made from the flesh or skin of the fruit.

How Papaya Extract is classified

Plant Extracts, Exfoliant

Recommendations for using Papaya Extract during pregnancy and breastfeeding

Limited data suggests no known risk

 

Papaya Extract During Pregnancy

What we know about using Papaya Extract while pregnant or breastfeeding

Limited information available.

The oral DART studies summarized below are described in Table 6. The effect of ripe papaya blend (500 mL papaya/L water) on different stages of pregnancy was studied in SpragueDawley rats by administering the test substance on days 1-5, days 6-11, days 12-17, and days 1-20 of gestation. 40 No signs of fetal or maternal toxicity were observed in any of the treatment groups. An aqueous Carica papaya leaf extract (60 or 120 mg/kg) was given to pregnant Wistar rats via gavage on days 12-18 of gestation. 41 Abnormalities in morphometry of fetuses was noted in rats treated with 60 mg/kg of the extract, while 100% resorption was noted in rats treated with 120 mg/kg of the extract. The effect of an aqueous extract of Carica papaya leaf on male fertility was evaluated in male Wistar rats.42 Treated rats were given 500 mg/kg bw extract orally for 21 days. Statistically significant reductions in mean values of sperm count, motility, viability, and serum testosterone concentration was noted in treated rats compared to control rats. In a different study, male rats were given 100, 200, or 400 mg/kg bw of a methanolic Carica papaya extract via gavage for 28 days.36 The mid- and high doses induced a significant decrease in rat sperm count. Sperm motility reduction was noted when an aqueous Carica papaya seed extract (50 mg/kg bw/day) was given to male albino mice for 10 to 30 days.43 The potential reproductive effects of an aqueous alkaloid extract of Carica papaya seeds (10, 50, and 150 mg/kg/day) was studied in male Wistar rats.44 Results showed that oral administration of Carica papaya seed extract prevents fertilization, reduces sperm cell counts, promotes sperm cell degeneration, and induces testicular cell lesions, in a dose-dependent manner. An aqueous Carica papaya seed extract was given orally to female Sprague-Dawley rats in doses of 50, 100, or 800 mg/kg bw/day.45 At all doses, a disruption of the normal sequences of the estrous cycle was observed. No treatment-related adverse effects were noted when aqueous Carica papaya seed extract was given to male New Zealand white rabbits, orally at doses of up to 100 mg/kg bw/day, for 150 days.46 Fertility, semen quality, and hematological parameters were similar among treated and control groups. Although papaya seed extract is not amo

General safety info about Papaya Extract from CIR

No report found.

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Products where you might find Papaya Extract

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