Pyrus Malus (Apple) Fruit Extract

The Basics On Pyrus Malus (Apple) Fruit Extract

What is Pyrus Malus (Apple) Fruit Extract?

Pyrus malus (apple) fruit extract is a species of apple; the fruit is a tremendous source of polyphenolic antioxidants.

What are other names for Pyrus Malus (Apple) Fruit Extract?

APPLE EXTRACT, APPLE FRUIT EXTRACT, APPLE, MALUS SYLVESTRIS, EXT., EXTRACT OF APPLE, EXTRACT OF APPLE FRUIT, EXTRACT OF PYRUS MALUS, PYRUS MALUS (APPLE) FRUIT EXTRACT, PYRUS MALUS EXTRACT, and PYRUS MALUS FRUIT EXTRACT

What is Pyrus Malus (Apple) Fruit Extract used for?

According to the Cosmetic Ingredient Review, apple-derived ingredients are used for the following functions: skin conditioning, emulsion stabilizing, increasing viscosity, as an astringent, fragrance, and exfoliant (1).

How Pyrus Malus (Apple) Fruit Extract is classified

Skin-Restoring, Plant Extracts, Texture Enhancer

Recommendations for using Pyrus Malus (Apple) Fruit Extract during pregnancy and breastfeeding

Limited data suggests no known risk

 

Pyrus Malus (Apple) Fruit Extract During Pregnancy

What we know about using Pyrus Malus (Apple) Fruit Extract while pregnant or breastfeeding

Limited information available.

Body weight gain was unaffected by treatment, and changes in food consumption were attributed to normal biological variation. Statistically significant differences (P < 0.05 or P < 0.01) in hematological, clinical chemistry, and urinary tests were reported. However, these changes were within the normal range of physiological background data and were not correlated with the apple polyphenol extract dosage. Gross necropsy findings were not indicative of adverse changes in any of the organs examined. A statistically significant increase in lung weight was found in the 1,000 mg/kg/day dose group, but this change was within the normal physiological range. Histopathological examination of organs did not reveal any changes that were related to dosing with the test material.Antimicrobial ActivityPyrus Malus (Apple) Pectin ExtractPectin was extracted from several varieties of apple, i.e., American, Delicious, and Maharaj-ji (all obtained from Kashmir).20 Pectin content was found to be maximum in Maharaj-ji (20.60%), followed by Delicious (14.4%) and American (11.60%). The pectin extracted was evaluated for in vitro antibacterial activity against different pathogenic bacterial cultures and antifungal activity. Pectin extracted from the Delicious variety had potent antibacterial activity against Klebsiella pneumonia(mean inhibitory concentration [MIC] = 0.8 mg/ml), followed by Streptococcus pyogenes(MIC = 0.3 mg/ml), E. coli(MIC = 0.7 mg/ml), and Lactococcussp. (MIC = 0.7 mg/ml). There was no evidence of antibacterial activity in any of the bacterial strains tested with pectin extracted from the other varieties. Regardless of the variety from which pectin wasextracted, there was no evidence of antifungal activity against the following fungal strains: Aspergillus niger, Candida albicans, or Saccharomyces cerevisiae.REPRODUCTIVE AND DEVELOPMENTAL TOXICITYData on the reproductive and developmental toxicity of apple-derived ingredients were not found in the published literature nor were unpublished data provided.GENOTOXICITYIn VitroApple Fruit ExtractThe genotoxicity of apple fruit extract was evaluated in the Ames test using Escherichia coli strain WP2uvrA and Salmonella typhimurium strains TA100, TA98, TA1535, and TA1537.10 The test material was evaluated at doses up to 5,000 μg/plate with and without metabolic activation. Slight genotoxicity was observed at a dose of 2,500 μg/plate without metabolic activation, but not at the other doses, with or without metabolic activation.Apple fruit extract (concentrations up to 0.313 mg/ml) was evaluated for genotoxic activity in Chinese hamster CHL/IU mammalian cells using a chromosomal aberrations assay with and without metabolic activation.10 Genotoxicity was not observed, with or without metabolic activation.Pyrus Malus (Apple) Seed ExtractThe genotoxicity of Pyrus Malus (Apple) Seed Extract (1% w/v in hexyldecanol) was studied using the following S. typhimurium strains: TA98, TA100, TA1535, TA1537, and TA1538.25 The test substance was evaluated at doses up to 5,000 μg/plate with and without metabolic activation. Revertant frequencies in treated strains tested were similar to vehicle control values. All positive control data were within acceptable ranges. The test substance was classified as non-genotoxic. Procyanidin B-2 The genotoxicity of procyanidin B-2 (> 94% pure) was evaluated using S. typhimurium strains TA98, TA100, TA1535, and TA1537, and E. colistrain WP2uvrA.9 Procyanidin B-2 was tested at doses up to 5,000, μg/plate with or without metabolic activation. Test results were negative.In the chromosome aberrations assay using Chinese hamster lung cells, procyanidin B-2 (> 94% pure) was evaluated with (concentrations up to 4.8 mM) and without (concentrations up to 1.8 mM) metabolic activation.9 Neither structural aberrations such as chromosome-type aberrations or chromatid-type aberrations were observed with or without metabolic activation. However, polyploidy was observed with metabolic activation.

General safety info about Pyrus Malus (Apple) Fruit Extract from CIR

The Cosmetic Ingredient Review (CIR) Expert Panel reviewed the safety of 26 apple-derived ingredients, which function mostly as skin conditioning agents in cosmetic products. Because apple-derived ingredients may be obtained from different apple cultivars, the composition of ingredients derived from different cultivars should be similar to that of ingredients reviewed in this safetyassessment. Additionally, industry should use good manufacturing practices to limit impurities that could be present in botanical ingredients. The Panel reviewed relevant data relating to the safety of these ingredients, and concluded that 21 ingredients are safe in the present practices of use and concentration in cosmetics as described in this safety assessment, when formulated to be non-irritating and non-sensitizing; the available data are insufficient for determining the safety of Pyrus Malus (Apple) Root Extract, Pyrus Malus (or Malus Domestica) (Apple) Stem Extract, Malus Domestica (Apple) Callus Extract, and Malus Domestica (Apple) Oil.

Use this, not that!

Products where you might find Pyrus Malus (Apple) Fruit Extract

emerginC Vitamin C Plus Retinol Mask (1.7 fl. oz.); Jan Marini Retinol Plus Mask (1.2 oz.); Shani Darden Skin Care Retinol Reform®; Shani Darden Skin Care Retinol Reform Mini