Cocamidopropyl Betaine

The Basics On Cocamidopropyl Betaine

What is Cocamidopropyl Betaine?

One of the more gentle surfactants used in skincare products.

What are other names for Cocamidopropyl Betaine?

1-PROPANAMINIUM, 3-AMINO-N-(CARBOXYMETHYL)-N,N-DIMETHYL-, N-COCO ACYL DERIVS., INNER SALTS, 1-PROPANAMINIUM, N-(CARBOXYMETHYL)-N,N-DIMETHYL-3-[(1-OXOCOCONUT)AMINO]-, HYDROXIDE, INNER SALT, 1PROPANAMINIUM, 3AMINON(CARBOXYMETHYL)N,NDIMETHYL, NCOCO ACYL DERIVS., HYDROXIDES, INNER SALTS, CADG, COCAMIDO BETAINE, COCAMIDOPROPYL BETAINE, COCAMIDOPROPYL DIMETHYL GLYCINE, COCOAMIDOPROPYL BETAINE, COCOYL AMIDE PROPYLBETAINE, COCOYL AMIDE PROPYLDI METHYL GLYCINE SOLUTION, COCOYL AMIDE PROPYLDIMETHYL GLYCINE, HYDROXIDE INNER SALT 1-PROPANAMINIUM, N-(CARBOXYMETHYL)-N,N-DIMETHYL-3-[(1-OXOCOCONUT)AMINO]-, HYDROXIDES INNER QUATERNARY AMMONIUM COMPOUNDS, (CARBOXYMETHYL)(3-COCOAMIDOPROPYL)DIMETHYL, INNER QUATERNARY AMMONIUM COMPOUNDS, (CARBOXYMETHYL)(3-COCOAMIDOPROPYL)DIMETHYL, HYDROXIDES, INNER SALT 1-PROPANAMINIUM, N-(CARBOXYMETHYL)-N,N-DIMETHYL-3-[(1-OXOCOCONUT)AMINO]-, HYDROXIDE, INNER SALT N-(CARBOXYMETHYL)-N,N-DIMETHYL-3-[(1-OXOCOCONUT)AMINO]-1-PROPANAMINIUM HYDROXIDE, N-(CARBOXYMETHYL)-N,N-DIMETHYL-3-[(1-OXOCOCONUT)AMINO]-1-PROPANAMINIUM HYDROXIDE, INNER SALT, N-COCAMIDOPROPYL-N,N-DIMETHYLGLYCINE, HYDROXIDE, INNER SALT; COCOAMIDOPROPYLBETAINE; N-(COCOAMIDOPROPYL)-N,N-DIMETHYL-N-CARBOXYMETHYL AMMONIUM, BETAINE; N-(3-COCOAMIDOPROPYL)-N,N-DIMETHYL-N-CARBOXYMET, and SALTS

What is Cocamidopropyl Betaine used for?

Coco Betaine (also know as Cocamidopropyl betaine, CAPB) is an amphoteric synthetic detergent that has been increasingly used in cosmetics and personal hygiene products1. Examples of products containing CAPB include shampoos, contact lens solutions, toothpaste detergents, makeup removers, bath gels, skin care products, cleansers, liquid soaps, antiseptics, and gynecologic and anal hygiene products) CAPB is used as a foam booster in shampoos2. It is a medium strength surfactant also used in bath products like hand soaps. It is also used in cosmetics as an emulsifying agent and thickener, and to reduce irritation purely ionic surfactants would cause. It also serves as an antistatic agent in hair conditioners, which most often does not irritate skin or mucous membranes. Some studies have indicated that Coco betaine it is an allergen3. It also has antiseptic properties, making it suitable for personal sanitary products. It is compatible with other cationic, anionic, and nonionic surfactants. CAPB is obtained as an aqueous solution in concentrations of about 30%.

How Cocamidopropyl Betaine is classified

Cleansing Agents

Recommendations for using Cocamidopropyl Betaine during pregnancy and breastfeeding

Limited data suggests no known risk

 

Cocamidopropyl Betaine During Pregnancy

What we know about using Cocamidopropyl Betaine while pregnant or breastfeeding

Limited information available.

Dermal reproductive and developmental toxicity studies of cetyl betaine in rabbits determined the maternal LOAEL to be 10 mg/kg/day due to decreased body weight gain and a maternal NOAEL could not be established. The developmental LOAEL was 40 mg/kg/day and the developmental NOAEL was 20 mg/kg/day. In oral reproductive and developmental toxicity studies of cetyl betaine in rats, the LOAEL for the dams was 50 mg/kg due to decreased body weight gain and a maternal NOAEL could not be calculated. The developmental LOAEL was 250 mg/kg and the developmental NOAEL was 150 mg/kg. In an oral C12-C14 alkyldimethyl betaines study, the reproductive NOEL was 150 mg/kg bw/day and the reproductive LOAEL was 300 mg/kg bw/day due to decreased pup weight and litter size and increased post-implantation loss and postnatal loss. Another oral C12-C14 alkyldimethyl betaines study determined the reproductive NOAEL to be 300 mg/kg/day when the test material was tested up to 1000 mg/kg/day.

General safety info about Cocamidopropyl Betaine from CIR

The Cosmetic Ingredient Review Expert Panel reviewed the product use, formulation and safety data of eleven alkyl betaines, which mostly function as hair and skin-conditioning agents. With the exception of betaine, alkyl betaines may also function as antistatic agents, surfactants-cleansing agents, and viscosity increasing agents in cosmetic products. Although there are data gaps, the shared chemical core structure, similar functions and concentrations in cosmetics, and the expected similarities in physicochemical properties, enabled grouping these ingredients and reading across the available toxicological data to support the safety assessment of each individual compound in the entire group. The Panel concluded alkyl betaines were safe as cosmetic ingredients in the present practices of use and concentration, when formulated to be non-irritating.

Use this, not that!

Products where you might find Cocamidopropyl Betaine

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