The Basics On Aspartic Acid
What is Aspartic Acid?
An α-amino acid that is used in the biosynthesis of proteins.
What are other names for Aspartic Acid?
(S)- BUTANEDIOIC ACID, AMINO-, AMINO- (S)- BUTANEDIOIC ACID, ASPARGIC ACID, ASPARGINIC ACID, ASPARTIC ACID, BUTANEDIOIC ACID, AMINO-, (S)-, L-AMINOSUCCINIC ACID, and L-ASPARTIC ACID
What is Aspartic Acid used for?
Acetyl aspartic acid, also known as N-Acetylaspartic acid, is a derivative of aspartic acid. It is the second most concentrated molecule in the brain after the amino acid glutamate1. Whilst it has been studied extensively for its effects on our metabolism, diseases and our health until recently there have been few studies on its impact on our skin health.
How Aspartic Acid is classified
Antioxidants, Skin-Replenishing
Recommendations for using Aspartic Acid during pregnancy and breastfeeding
Limited data suggests no known risk
Aspartic Acid During Pregnancy
What we know about using Aspartic Acid while pregnant or breastfeeding
Limited information available.
N/A
General safety info about Aspartic Acid from CIR
The Cosmetic Ingredient Review Expert Panel reviewed the safety of α-amino acids, which function primarily as hair and skin conditioning agents in cosmetic products. The safety of α-amino acids as direct food additives has been well established based on extensive research through acute and chronic dietary exposures. The Panel focused its review on dermal irritation and sensitization data relevant to the use of these ingredients in topical cosmetics. The Panel concluded that α-amino acids were safe as cosmetic ingredients in the practices of use and concentration of this safety assessment.
Use this, not that!
Products where you might find Aspartic Acid
NuFACE NuFACE Trinity Complete Facial Toning Kit (4 piece); Luzern Laboratories Force de Vie Creme Intensive (2 fl. oz.); Oribe Gold Lust Repair & Restore Conditioner (33.8 fl. oz.); RevitaLash Cosmetics Advanced Eyelash Conditioner Р6 Month Supply (0.118 fl. oz.)l; Luzern Laboratories Force De Vie Pure Oxygen Creme Luxe (2 fl. oz.); N/A
List of References
General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
1. N-Acetyl-L-aspartic_acid-Pharmacology and Biochemistry. PubChem- Open Chemistry Database. https://pubchem.ncbi.nlm.nih.gov/compound/N-Acetyl-L-aspartic_acid#section=Pharmacology-and-Biochemistry. Published 2018. Accessed October 2018. 2. Gillbro J, Merinville E, Cattley K, et al. In vivo topical application of acetyl aspartic acid increases fibrillin-1 and collagen IV deposition leading to a significant improvement of skin firmness. Int J Cosmet Sci. 2015;37 Suppl 1:41-46. [PubMed] 3. Mavon A. Acetyl aspartic acid, a novel active ingredient, demonstrates potential to improve signs of skin ageing: from consumer need to clinical proof. Int J Cosmet Sci. 2015;37 Suppl 1:1-2. [PubMed] 4. Duracher L, Visdal-Johnsen L, Mavon A. In vitro and in vivo dermal absorption assessment of acetyl aspartic acid: a compartmental study. Int J Cosmet Sci. 2015;37 Suppl 1:34-40. [PubMed] 5. N-Acetyl-L-aspartic acid – Safety and Hazards. PubChem- Open Chemistry Database. https://pubchem.ncbi.nlm.nih.gov/compound/N-Acetyl-L-aspartic_acid#section=Safety-and-Hazards. Published 2018. Accessed October 2018. 6. Daly P, Moran G. Safety assessment of a novel active ingredient, acetyl aspartic acid, according to the EU Cosmetics Regulation and the Scientific Committee on Consumer Safety guidelines. Int J Cosmet Sci. 2015;37 Suppl 1:21-27. [PubMed]
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
