The Basics
What is Abciximab?
Used to lessen the chance of heart attack in people who need percutaneous coronary intervention (PCI).
Brand names for Abciximab
Reopro
How Abciximab is classified
Antibodies – Monoclonal, Anticoagulants, Immunoglobulin Fab Fragments, Platelet Aggregation Inhibitors
Abciximab During Pregnancy
Abciximab pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Abciximab while pregnant
N/A
Taking Abciximab While Breastfeeding
What are recommendations for lactation if you're taking Abciximab?
No information is available on the clinical use of abciximab during breastfeeding. Because abciximab is a large protein molecule with a molecular weight of 47,615, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant’s gastrointestinal tract. Until more data become available, abciximab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. If it is used by a nursing mother, monitor the infant for bruising and bleeding.
Maternal / infant drug levels
No information is available on the clinical use of abciximab during breastfeeding. Because abciximab is a large protein molecule with a molecular weight of 47,615, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant’s gastrointestinal tract. Until more data become available, abciximab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. If it is used by a nursing mother, monitor the infant for bruising and bleeding.
Possible effects of Abciximab on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Abciximab
None listed
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
