The Basics

What is Aloe / Aloe vera?

Used in treating skin conditions, like psoriasis and acne; has a calming effect on the skin and have been shown to help reduce itchiness and inflammation.

Brand names for Aloe / Aloe vera

N/A

How Aloe / Aloe vera is classified

Complementary Therapies, Phytotherapy, Plants, Medicinal

Aloe / Aloe vera During Pregnancy

Aloe / Aloe vera pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Aloe / Aloe vera while pregnant

N/A

Taking Aloe / Aloe vera While Breastfeeding

What are recommendations for lactation if you're taking Aloe / Aloe vera?

Aloe vera gel consists of the clear gel from the center of fresh leaves of Aloe vera and related aloes. Active ingredients include mono- and polysaccharides (e.g., acemannan, glucomannan), allantoin, enzymes (e.g., cyclooxygenase, amylase, lipase, alkaline phosphatase, carboxypeptidase), and salicylic acid. It should not be confused with Aloe latex which comes from the inner portion of the skin and contains potent anthraquinone laxatives. Aloe vera gel has been used topically on the nipples during nursing to help heal cracked nipples. In a randomized, single-blinded study (investigators blinded), aloe vera was more effective than lanolin in decreasing nipple pain score after 7 days in women with sore nipples postpartum.[1] Another study compared breastmilk alone applied to the nipples after breastfeeding to either olive oil or aloe vera gel. All had less pain after 7 days of nursing, but the decrease on pain was greater with aloe vera than with the other treatments.[2] Topical aloe has also been combined with a cactus leaf preparation and massage to treat engorgement.[3] If aloe vera is applied to the nipples, it should be washed off before nursing the infant because the taste might adversely affect nursing or cause diarrhea in the infant.[4][5] No data exist on the safety and efficacy of Aloe vera gel in nursing mothers or infants. Aloe vera gel has caused itching, burning, and allergic contact dermatitis, possibly from contamination with the irritating latex from the leaves.[6][7] Aloe vera gel also has an antiplatelet effect and can enhance the antiplatelet effect of other drugs. Aloe latex, the laxative, should not be used during breastfeeding.[8][9] Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products.

Maternal / infant drug levels

Aloe vera gel consists of the clear gel from the center of fresh leaves of Aloe vera and related aloes. Active ingredients include mono- and polysaccharides (e.g., acemannan, glucomannan), allantoin, enzymes (e.g., cyclooxygenase, amylase, lipase, alkaline phosphatase, carboxypeptidase), and salicylic acid. It should not be confused with Aloe latex which comes from the inner portion of the skin and contains potent anthraquinone laxatives. Aloe vera gel has been used topically on the nipples during nursing to help heal cracked nipples. In a randomized, single-blinded study (investigators blinded), aloe vera was more effective than lanolin in decreasing nipple pain score after 7 days in women with sore nipples postpartum.[1] Another study compared breastmilk alone applied to the nipples after breastfeeding to either olive oil or aloe vera gel. All had less pain after 7 days of nursing, but the decrease on pain was greater with aloe vera than with the other treatments.[2] Topical aloe has also been combined with a cactus leaf preparation and massage to treat engorgement.[3] If aloe vera is applied to the nipples, it should be washed off before nursing the infant because the taste might adversely affect nursing or cause diarrhea in the infant.[4][5] No data exist on the safety and efficacy of Aloe vera gel in nursing mothers or infants. Aloe vera gel has caused itching, burning, and allergic contact dermatitis, possibly from contamination with the irritating latex from the leaves.[6][7] Aloe vera gel also has an antiplatelet effect and can enhance the antiplatelet effect of other drugs. Aloe latex, the laxative, should not be used during breastfeeding.[8][9] Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products.

Possible effects of Aloe / Aloe vera on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Aloe / Aloe vera

None listed

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Saeidi R, Tafazoli M, Gholami M et al. New treatment for nipple soreness in breastfeeding mothers: A clinical trial study. Iran J Neonatol. 2015;6:48-51. http://ijn.mums.ac.ir/issue_626_671_Volume+6%2C+Issue+2%2C+Spring+2015.html
2. Eshgizade M , Moghaddam MB, Moghaddam HM et al. A comparison of the efficacy of olive oil, aloe vera extract and breast milk on healing breast fissure in the breastfeeding women. Avicenna J Phytomedicine. 2015;5:86-7. Abstract.
3. Meng S, Deng Q, Feng C et al. Effects of massage treatment combined with topical cactus and aloe on puerperal milk stasis. Breast Dis. 2015;35:173-8. PMID: 25881639
4. Yarnell E. Botanical medicine in pregnancy and lactation. Altern Complement Ther. 1997;3 (April):93-100.
5. Larimore WL, Petrie KA. Drug use during pregnancy and lactation. Primary Care. 2000;27:35-53.
6. Barankin B, Gross MS. Nipple and areolar eczema in the breastfeeding woman. J Cutan Med Surg. 2004;8:126-30. PMID: 15129318
7. De Smet PA. Health risks of herbal remedies: an update. Clin Pharmacol Ther. 2004;76:1-17. PMID: 15229459
8. Kopec K. Herbal medications and breastfeeding. J Hum Lact. 1999;15:157-61. PMID: 10578793
9. Nice F, Coghlan RJ, Birmingham BT. Which herbals are safe to take while breastfeeding? Here’s a guide to popular herbs and their potential risk to nurslings. US Pharm. 2000;25.

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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