The Basics
What is Antihemophilic Factor?
Ued to treat and prevent serious bleeding episodes in patients with hemophilia A.
Brand names for Antihemophilic Factor
Alphanate
How Antihemophilic Factor is classified
Blood Coagulation Factors, Coagulants
Antihemophilic Factor During Pregnancy
Antihemophilic Factor pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Antihemophilic Factor while pregnant
Animal reproduction studies have not been conducted with ALPHANATE. It is also not known whether ALPHANATE can cause fetal harm when administered to a pregnant woman or affect reproductive capacity. ALPHANATE should be given to a pregnant woman only if clearly needed.
Taking Antihemophilic Factor While Breastfeeding
What are recommendations for lactation if you're taking Antihemophilic Factor?
No information is available on the clinical use of antihemophilic factor (coagulation factor VIII) during breastfeeding. Because it is a large protein molecule, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant’s gastrointestinal tract. Until more data become available, antihemophilic factor should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.
Maternal / infant drug levels
No information is available on the clinical use of antihemophilic factor (coagulation factor VIII) during breastfeeding. Because it is a large protein molecule, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant’s gastrointestinal tract. Until more data become available, antihemophilic factor should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.
Possible effects of Antihemophilic Factor on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Antihemophilic Factor
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
