The Basics
What is Antipyrine?
Often used to test effects of other drugs on liver enzymes. In combination with benzocaine in otic solutions, used to relieve ear pain and swelling caused by middle ear infections.
Brand names for Antipyrine
Ab Otic, Aurodex, Auroto, Benzotic, Dec-Agesic Ab, Dolotic
How Antipyrine is classified
Anti-Inflammatory Agents – Non-Steroidal
Antipyrine During Pregnancy
Antipyrine pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Antipyrine while pregnant
N/A
Taking Antipyrine While Breastfeeding
What are recommendations for lactation if you're taking Antipyrine?
Antipyrine is considered unlikely to harm the infant.[1] Because antipyrine is available only in ear drops, it is unlikely to be absorbed by the mother and reach the breastmilk. No special precautions are required during maternal use of antipyrine-containing ear drops.
Maternal / infant drug levels
Antipyrine is considered unlikely to harm the infant.[1] Because antipyrine is available only in ear drops, it is unlikely to be absorbed by the mother and reach the breastmilk. No special precautions are required during maternal use of antipyrine-containing ear drops.
Possible effects of Antipyrine on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Antipyrine
None listed
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Berlin CM Jr, Vesell ES. Antipyrine disposition in milk and saliva of lactating women. Clin Pharmacol Ther. 1982;31:38-44. PMID: 7053302
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
