The Basics

What is Atovaquone?

Used to treat Pneumocystis jiroveci pneumonia.

Brand names for Atovaquone

Mepron

How Atovaquone is classified

Anti-infective Agents, Antiparasitic Agents, Antimalarials, Antiprotozoal Agents

Atovaquone During Pregnancy

Atovaquone pregnancy category

Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Atovaquone while pregnant

N/A

Taking Atovaquone While Breastfeeding

What are recommendations for lactation if you're taking Atovaquone?

No information is available on the use of atovaquone during breastfeeding. However, the quantity of drug in breast milk is assumed too low to provide adequate protection against malaria for the breastfed infant.[1] A dosage has been established for infants weighing as little as 5 kg, so it is unlikely to adversely affect breastfed infants weighing 5 kg or more.

Maternal / infant drug levels

No information is available on the use of atovaquone during breastfeeding. However, the quantity of drug in breast milk is assumed too low to provide adequate protection against malaria for the breastfed infant.[1] A dosage has been established for infants weighing as little as 5 kg, so it is unlikely to adversely affect breastfed infants weighing 5 kg or more.

Possible effects of Atovaquone on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Atovaquone

Chloroquine, Mefloquine.

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Centers for Disease Control and Prevention. CDC Yellow Book 2018: Health Information for International Travel. New York: Oxford University Press. 2017. https://wwwnc.cdc.gov/travel/page/2018-yellow-book-about

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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