Basiliximab

The Basics

What is Basiliximab?

Used to prevent organ transplant rejection, especially in kidney transplants.

Brand names for Basiliximab

Basiliximab

How Basiliximab is classified

Antibodies – Monoclonal

Basiliximab During Pregnancy

Basiliximab pregnancy category

Category BNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Basiliximab while pregnant

N/A

Taking Basiliximab While Breastfeeding

What are recommendations for lactation if you're taking Basiliximab?

No information is available on the clinical use of basiliximab during breastfeeding. Because basiliximab is a large protein molecule with a molecular weight of about 144,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant’s gastrointestinal tract. Until more data become available, basiliximab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. The manufacturer recommends that breastfeeding be discontinued during basiliximab therapy.

Maternal / infant drug levels

No information is available on the clinical use of basiliximab during breastfeeding. Because basiliximab is a large protein molecule with a molecular weight of about 144,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant’s gastrointestinal tract. Until more data become available, basiliximab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. The manufacturer recommends that breastfeeding be discontinued during basiliximab therapy.

Possible effects of Basiliximab on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Basiliximab

None listed