The Basics

What is Bendroflumethiazide?

A diuretic used to treat high blood pressure (hypertension) and the build-up of fluid in your body

Brand names for Bendroflumethiazide

Corzide

How Bendroflumethiazide is classified

Antihypertensive Agents, Thiazide Diuretics

Bendroflumethiazide During Pregnancy

Bendroflumethiazide pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Bendroflumethiazide while pregnant

Thiazides cross the placental barrier and appear in cord blood. The use of thiazides in pregnant women requires that the anticipated benefit be weighed against possible hazards to the fetus. These hazards include fetal or neonatal jaundice, thrombocytopenia, and possibly other adverse reactions which have occurred in the adult.

Taking Bendroflumethiazide While Breastfeeding

What are recommendations for lactation if you're taking Bendroflumethiazide?

No information is available on the amount of bendroflumethiazide in breastmilk. Intense diuresis with large doses of bendroflumethiazide can decrease breastmilk production, especially during the neonatal period. Shorter-acting diuretics in low doses are preferred over bendroflumethiazide.

Maternal / infant drug levels

No information is available on the amount of bendroflumethiazide in breastmilk. Intense diuresis with large doses of bendroflumethiazide can decrease breastmilk production, especially during the neonatal period. Shorter-acting diuretics in low doses are preferred over bendroflumethiazide.

Possible effects of Bendroflumethiazide on milk supply

Bendroflumethiazide has been used to suppress lactation in oral doses of 5 mg twice daily for 5 days,[1] and in doses of 10 mg in the morning and 5 mg in the afternoon.[2] The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of potent diuretics on established, ongoing lactation.

Possible alternatives to Bendroflumethiazide

Chlorothiazide, Hydrochlorothiazide.

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Healy M. Suppressing lactation with oral diuretics. Lancet. 61;1:1353-4.
2. Stout G. Suppression of lactation. Br Med J. 62;1:1150. Letter. PMC: PMC1958377

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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