Bimatoprost

The Basics

What is Bimatoprost?

Used to treat high pressure inside the eye due to glaucoma (open-angle type) or other eye diseases (e.g., ocular hypertension).

Brand names for Bimatoprost

Latisse, Lumigan

How Bimatoprost is classified

Antiglaucoma Agents, Prostaglandins

Bimatoprost During Pregnancy

Bimatoprost pregnancy category

Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Bimatoprost while pregnant

In embryo/fetal developmental studies in pregnant mice and rats, abortion was observed at oral doses of bimatoprost which achieved at least 33 or 97 times, respectively, the maximum intended human exposure based on blood AUC levels. At doses at least 41 times the maximum intended human exposure based on blood AUClevels, the gestation length was reduced in the dams, the incidence of dead fetuses, late resorptions, peri- and postnatal pup mortality was increased, and pup body weights were reduced.There are no adequate and well-controlled studies of LUMIGAN® 0.01% and 0.03%(bimatoprost ophthalmic solution) administration in pregnant women. Because animalreproductive studies are not always predictive of human response LUMIGAN® should beadministered during pregnancy only if the potential benefit justifies the potential risk tothe fetus.

Taking Bimatoprost While Breastfeeding

What are recommendations for lactation if you're taking Bimatoprost?

No information is available on the use of bimatoprost during breastfeeding. Because of its short half-life it is not likely to reach the bloodstream of the infant or cause any adverse effects in breastfed infants. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

Maternal / infant drug levels

No information is available on the use of bimatoprost during breastfeeding. Because of its short half-life it is not likely to reach the bloodstream of the infant or cause any adverse effects in breastfed infants. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

Possible effects of Bimatoprost on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Bimatoprost

None listed