The Basics
What is Ceftibuten?
Used to treat certain infections caused by bacteria such as bronchitis; and infections of the ears, throat, and tonsils.
Brand names for Ceftibuten
Cedax
How Ceftibuten is classified
Anti-Infective Agents, Antibacterial Agents, Cephalosporins
Ceftibuten During Pregnancy
Ceftibuten pregnancy category
Category BNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Ceftibuten while pregnant
Ceftibuten was not teratogenic in the pregnant rat at oral doses up to 400 mg/kg/day (approximately 8.6 times the human dose based on mg/m2/day). Ceftibuten was not teratogenic in the pregnant rabbit at oral doses up to 40 mg/kg/day (approximately 1.5 times the human dose based on mg/m2/day) and has revealed no evidence of harm to the fetus. There are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
Taking Ceftibuten While Breastfeeding
What are recommendations for lactation if you're taking Ceftibuten?
Limited information indicates that ceftibuten produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant’s gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. Ceftibuten is acceptable in nursing mothers.
Maternal / infant drug levels
Limited information indicates that ceftibuten produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant’s gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. Ceftibuten is acceptable in nursing mothers.
Possible effects of Ceftibuten on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Ceftibuten
None listed
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Barr WH, Lin CC, Radwanski E et al. The pharmacokinetics of ceftibuten in humans. Diagn Microbiol Infect Dis. 1991;14:93-100. PMID: 2013216
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
