The Basics
What is Cyanocobalamin Co 57?
Indicated in the diagnosis of pernicious anemia.
Brand names for Cyanocobalamin Co 57
Cyanocobalamin
How Cyanocobalamin Co 57 is classified
Diagnostic Agents, Radiopharmaceuticals, Diagnostic Agents
Cyanocobalamin Co 57 During Pregnancy
Cyanocobalamin Co 57 pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Cyanocobalamin Co 57 while pregnant
Adequate and well-controlled studies have not been done in pregnant women. However, vitamin B12 is an essential vitamin and requirements are increased during pregnancy. Amounts of vitamin B12 that are recommended by the Food and Nutrition Board, National Academy of Science-National Research Council for pregnant women (4 mcg daily) should be consumed during pregnancy.
Taking Cyanocobalamin Co 57 While Breastfeeding
What are recommendations for lactation if you're taking Cyanocobalamin Co 57?
Information in this record refers to the use of cyanocobalamin Co 57 as a diagnostic agent. Limited data indicate that excretion of radioactivity into breastmilk following cyanocobalamin Co 57 is low and does not require withholding of breastfeeding after diagnostic use. However, to minimize the radiation dose to the infant, some authors suggest that previously saved milk could be substituted for one feeding at about 24 hours after the dose.[1] Mothers concerned about the level of radioactivity in their milk could ask to have it tested at a nuclear medicine facility at their hospital. When the radioactivity is at a safe level she may resume breastfeeding. A method for measuring milk radioactivity and determining the time when a mother can safely resume breastfeeding has been published.[2]
Maternal / infant drug levels
Information in this record refers to the use of cyanocobalamin Co 57 as a diagnostic agent. Limited data indicate that excretion of radioactivity into breastmilk following cyanocobalamin Co 57 is low and does not require withholding of breastfeeding after diagnostic use. However, to minimize the radiation dose to the infant, some authors suggest that previously saved milk could be substituted for one feeding at about 24 hours after the dose.[1] Mothers concerned about the level of radioactivity in their milk could ask to have it tested at a nuclear medicine facility at their hospital. When the radioactivity is at a safe level she may resume breastfeeding. A method for measuring milk radioactivity and determining the time when a mother can safely resume breastfeeding has been published.[2]
Possible effects of Cyanocobalamin Co 57 on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Cyanocobalamin Co 57
None listed
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Pomeroy KM, Sawyer LJ, Evans MJ. Estimated radiation dose to breast feeding infant following maternal administration of 57Co labelled to vitamin B12. Nucl Med Commun. 2005;26:839-41. PMID: 16096589
2. Stabin MG, Breitz HB. Breast milk excretion of radiopharmaceuticals: mechanisms, findings, and radiation dosimetry. J Nucl Med. 2000;41:863-73. PMID: 10809203
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
