The Basics

What is Dactinomycin?

approved by FDA for the treatment of different cancer conditions among which are Ewing’s sarcoma, Wilm’s tumor, gestational trophoblastic disease

Brand names for Dactinomycin

Cosmegen

How Dactinomycin is classified

Antineoplastic Agents, Antibiotics, Antineoplastic, Protein Synthesis Inhibitors, Nucleic Acid Synthesis Inhibitors

Dactinomycin During Pregnancy

Dactinomycin pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Dactinomycin while pregnant

N/A

Taking Dactinomycin While Breastfeeding

What are recommendations for lactation if you're taking Dactinomycin?

No information is available on the use of dactinomycin during breastfeeding. Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy. The manufacturer recommends that breastfeeding be discontinued during dactinomycin therapy and for 14 days after the last dose.

Maternal / infant drug levels

No information is available on the use of dactinomycin during breastfeeding. Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy. The manufacturer recommends that breastfeeding be discontinued during dactinomycin therapy and for 14 days after the last dose.

Possible effects of Dactinomycin on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Dactinomycin

None listed

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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