The Basics
What is Dactinomycin?
approved by FDA for the treatment of different cancer conditions among which are Ewing’s sarcoma, Wilm’s tumor, gestational trophoblastic disease
Brand names for Dactinomycin
Cosmegen
How Dactinomycin is classified
Antineoplastic Agents, Antibiotics, Antineoplastic, Protein Synthesis Inhibitors, Nucleic Acid Synthesis Inhibitors
Dactinomycin During Pregnancy
Dactinomycin pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Dactinomycin while pregnant
N/A
Taking Dactinomycin While Breastfeeding
What are recommendations for lactation if you're taking Dactinomycin?
No information is available on the use of dactinomycin during breastfeeding. Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy. The manufacturer recommends that breastfeeding be discontinued during dactinomycin therapy and for 14 days after the last dose.
Maternal / infant drug levels
No information is available on the use of dactinomycin during breastfeeding. Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy. The manufacturer recommends that breastfeeding be discontinued during dactinomycin therapy and for 14 days after the last dose.
Possible effects of Dactinomycin on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Dactinomycin
None listed
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.