The Basics
What is Dapagliflozin?
helps treat type 2 diabetes
Brand names for Dapagliflozin
Farxiga
How Dapagliflozin is classified
Hypoglycemic Agents, Sodium-Glucose Cotransporter 2 Inhibitors, SGLT2 Inhibitors
Dapagliflozin During Pregnancy
Dapagliflozin pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Dapagliflozin while pregnant
N/A
Taking Dapagliflozin While Breastfeeding
What are recommendations for lactation if you're taking Dapagliflozin?
No information is available on the clinical use of dapagliflozin during breastfeeding. Dapagliflozin is an uncharged molecule that is 91% protein bound in plasma, so it is unlikely to pass into breastmilk in clinically important amounts. The manufacturer does not recommend dapagliflozin during breastfeeding because of a theoretical risk to the infant’s developing kidney. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Maternal / infant drug levels
No information is available on the clinical use of dapagliflozin during breastfeeding. Dapagliflozin is an uncharged molecule that is 91% protein bound in plasma, so it is unlikely to pass into breastmilk in clinically important amounts. The manufacturer does not recommend dapagliflozin during breastfeeding because of a theoretical risk to the infant’s developing kidney. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Possible effects of Dapagliflozin on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Dapagliflozin
Acarbose, Glipizide, Glyburide, Insulin, Metformin, Miglitol.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.