The Basics
What is Dexrazoxane?
used to treat tissue damage caused by the leakage of certain cancer medicines from the injection site
Brand names for Dexrazoxane
Totect, Zinecard
How Dexrazoxane is classified
Antineoplastic Agents, Cardiotonic Agents, Enzyme Inhibitors, Topoisomerase II Inhibitors
Dexrazoxane During Pregnancy
Dexrazoxane pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Dexrazoxane while pregnant
N/A
Taking Dexrazoxane While Breastfeeding
What are recommendations for lactation if you're taking Dexrazoxane?
No information is available on the use of dexrazoxane during breastfeeding. The manufacturer recommends that women not breastfeed during treatment and for 2 weeks following the final dose of dexrazoxane. However, because dexrazoxane is used with doxorubicin, the abstinence period might be longer, depending on the doxorubicin dose.
Maternal / infant drug levels
No information is available on the use of dexrazoxane during breastfeeding. The manufacturer recommends that women not breastfeed during treatment and for 2 weeks following the final dose of dexrazoxane. However, because dexrazoxane is used with doxorubicin, the abstinence period might be longer, depending on the doxorubicin dose.
Possible effects of Dexrazoxane on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Dexrazoxane
None listed
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
