The Basics
What is Edrophonium?
Used to differentiate myasthenia gravis from cholinergic crisis and Lambert-Eaton.
Brand names for Edrophonium
Enlon Plus
How Edrophonium is classified
Cholinesterase Inhibitors, Diagnostic Agents, Parasympathomimetics
Edrophonium During Pregnancy
Edrophonium pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Edrophonium while pregnant
Animal reproduction studies have not been conducted with ENLON-PLUS (edrophonium chloride and atropine sulfate) . It is also not known whether ENLON-PLUS (edrophonium chloride and atropine sulfate) can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. ENLON-PLUS (edrophonium chloride and atropine sulfate) should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Taking Edrophonium While Breastfeeding
What are recommendations for lactation if you're taking Edrophonium?
No information is available on the use of edrophonium during breastfeeding. However, because of its short half-life and quaternary ammonium structure, it is unlikely to be excreted into breastmilk or orally absorbed by the infant. Administering the drug just after breastfeeding and waiting 2 to 3 hours before breastfeeding again should avoid any adverse reactions in the infant.
Maternal / infant drug levels
No information is available on the use of edrophonium during breastfeeding. However, because of its short half-life and quaternary ammonium structure, it is unlikely to be excreted into breastmilk or orally absorbed by the infant. Administering the drug just after breastfeeding and waiting 2 to 3 hours before breastfeeding again should avoid any adverse reactions in the infant.
Possible effects of Edrophonium on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Edrophonium
None listed
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
