The Basics
What is Emicizumab?
Used for routine prophylaxis to prevent or reduce the frequency of bleeding episodes in adults and children with hemophilia A with or without factor VIII inhibitors.
Brand names for Emicizumab
Hemlibra
How Emicizumab is classified
Antibodies – Monoclonal, Antineoplastic Agents
Emicizumab During Pregnancy
Emicizumab pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Emicizumab while pregnant
N/A
Taking Emicizumab While Breastfeeding
What are recommendations for lactation if you're taking Emicizumab?
No information is available on the clinical use of emicizumab during breastfeeding. Because emicizumab is a large protein molecule with a molecular weight of 145,600, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant’s gastrointestinal tract.
Maternal / infant drug levels
No information is available on the clinical use of emicizumab during breastfeeding. Because emicizumab is a large protein molecule with a molecular weight of 145,600, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant’s gastrointestinal tract.
Possible effects of Emicizumab on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Emicizumab
None listed
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
