The Basics
What is Factor Xa (recombinant), Inactivated-zhzo?
Approved for use in patients treated with the factor Xa inhibitors apixaban and rivaroxaban when acute reversal of anticoagulation is needed.
Brand names for Factor Xa (recombinant), Inactivated-zhzo
N/A
How Factor Xa (recombinant), Inactivated-zhzo is classified
Blood Coagulation Factors, Coagulants
Factor Xa (recombinant), Inactivated-zhzo During Pregnancy
Factor Xa (recombinant), Inactivated-zhzo pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Factor Xa (recombinant), Inactivated-zhzo while pregnant
N/A
Taking Factor Xa (recombinant), Inactivated-zhzo While Breastfeeding
What are recommendations for lactation if you're taking Factor Xa (recombinant), Inactivated-zhzo?
No information is available on the clinical use of coagulation factor Xa during breastfeeding. Because it is a large protein molecule with a molecular weight of about 40,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant’s gastrointestinal tract. Until more data become available, coagulation factor X should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.
Maternal / infant drug levels
No information is available on the clinical use of coagulation factor Xa during breastfeeding. Because it is a large protein molecule with a molecular weight of about 40,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant’s gastrointestinal tract. Until more data become available, coagulation factor X should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.
Possible effects of Factor Xa (recombinant), Inactivated-zhzo on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Factor Xa (recombinant), Inactivated-zhzo
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
