Gilteritinib

The Basics

What is Gilteritinib?

Used to treat a certain type of acute myeloid leukemia (AML) that has worsened or returned after treatment with other chemotherapy medications.

Brand names for Gilteritinib

N/A

How Gilteritinib is classified

Antineoplastic Agents, Enzyme Inhibitors, Protein Kinase Inhibitors, Signal Transduction Inhibitors, Tyrosine Kinase Inhibitors

Gilteritinib During Pregnancy

Gilteritinib pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Gilteritinib while pregnant

N/A

Taking Gilteritinib While Breastfeeding

What are recommendations for lactation if you're taking Gilteritinib?

No information is available on gilteritinib during breastfeeding. It is 94% bound to plasma proteins, so amounts in milk are likely to be low; however, it has a long half-life of about 113 hours. The manufacturer recommends that breastfeeding be discontinued during gilteritinib therapy and for 2 months after the last dose.

Maternal / infant drug levels

No information is available on gilteritinib during breastfeeding. It is 94% bound to plasma proteins, so amounts in milk are likely to be low; however, it has a long half-life of about 113 hours. The manufacturer recommends that breastfeeding be discontinued during gilteritinib therapy and for 2 months after the last dose.

Possible effects of Gilteritinib on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Gilteritinib

None listed