The Basics
What is Hydroflumethiazide?
Used to treat hypertension and edema.
Brand names for Hydroflumethiazide
Diucardin
How Hydroflumethiazide is classified
Antihypertensive Agents
Hydroflumethiazide During Pregnancy
Hydroflumethiazide pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Hydroflumethiazide while pregnant
Animal reproduction studies have not been conducted with Diucardin (hydroflumethiazide) . It is also not known whether Diucardin (hydroflumethiazide) can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Diucardin (hydroflumethiazide) should be given to a pregnant woman only if clearly needed. Nonteratogenic Effects Fetal or neonatal jaundice, thrombocytopenia, and possibly other adverse reactions which have occurred in the adult.
Taking Hydroflumethiazide While Breastfeeding
What are recommendations for lactation if you're taking Hydroflumethiazide?
No information is available on the amount of hydroflumethiazide in breastmilk. Intense diuresis with large doses may decrease breastmilk production. Other diuretics in low doses are preferred over hydroflumethiazide.
Maternal / infant drug levels
No information is available on the amount of hydroflumethiazide in breastmilk. Intense diuresis with large doses may decrease breastmilk production. Other diuretics in low doses are preferred over hydroflumethiazide.
Possible effects of Hydroflumethiazide on milk supply
Relevant published information on hydroflumethiazide was not found as of the revision date. Intense diuresis with thiazides and thiazide-like diuretics, fluid restriction and breast binding have been used to suppress postpartum lactation.[1][2][3] The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of diuretics on established, ongoing lactation.
Possible alternatives to Hydroflumethiazide
Chlorothiazide, Hydrochlorothiazide.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;277:1353-4.
2. Reiher KH. [Suppression of lactation by stimulation of diuresis]. Zentralbl Gynakol. 1963;85:188-90. PMID: 13973786
3. Stout G. Suppression of lactation. Br Med J. 1962;1:1150. Letter. PMC: PMC1958377
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
