The Basics
What is Isocarboxazid?
Treats depression by restoring the balance of neurotransmitters.
Brand names for Isocarboxazid
Marplan
How Isocarboxazid is classified
Antidepressive Agents, Monoamine Oxidase Inhibitors
Isocarboxazid During Pregnancy
Isocarboxazid pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Isocarboxazid while pregnant
The potential reproductive toxicity of isocarboxazid has not been adequately evaluated in animals. It is also not known whether isocarboxazid can cause embryo/fetal harm when administered to a pregnant woman or can affect reproductive capacity. Marplan should be given to a pregnant woman only if clearly needed.
Taking Isocarboxazid While Breastfeeding
What are recommendations for lactation if you're taking Isocarboxazid?
Because of the lack of data on use during breastfeeding, other antidepressants are preferred during breastfeeding.
Maternal / infant drug levels
Because of the lack of data on use during breastfeeding, other antidepressants are preferred during breastfeeding.
Possible effects of Isocarboxazid on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Isocarboxazid
Nortriptyline, Paroxetine, Sertraline.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
