The Basics
What is Lormetazepam?
hypnotic benzodiazepine and is officially indicated for moderate to severe insomnia
Brand names for Lormetazepam
Noctamid
How Lormetazepam is classified
Hypnotics and Sedatives, Anti-Anxiety Agents, Benzodiazepines
Lormetazepam During Pregnancy
Lormetazepam pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Lormetazepam while pregnant
N/A
Taking Lormetazepam While Breastfeeding
What are recommendations for lactation if you're taking Lormetazepam?
Lormetazepam is not approved for marketing in the United States by the U.S. Food and Drug Administration. Lormetazepam has low levels in breastmilk and a short half-life relative to many other benzodiazepines. Limited evidence from nursing mothers indicates that lorazepam does not cause any adverse effects in breastfed infants with usual maternal dosages. No special precautions are required.
Maternal / infant drug levels
Lormetazepam is not approved for marketing in the United States by the U.S. Food and Drug Administration. Lormetazepam has low levels in breastmilk and a short half-life relative to many other benzodiazepines. Limited evidence from nursing mothers indicates that lorazepam does not cause any adverse effects in breastfed infants with usual maternal dosages. No special precautions are required.
Possible effects of Lormetazepam on milk supply
Possible alternatives to Lormetazepam
Lorazepam, Midazolam, Oxazepam.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Humpel M, Stoppelli I, Milia S, Rainer E. Pharmacokinetics and biotransformation of the new benzodiazepine, lormetazepam, in man. III. Repeated administration and transfer to neonates via breast milk. Eur J Clin Pharmacol. 1982;21:421-5. PMID: 6122580
2. Lemmer P, Schneider S, Muhe A, Wennig R. Quantification of lorazepam and lormetazepam in human breast milk using GC-MS in the negative chemical ionization mode. J Anal Toxicol. 2007;31:224-6. PMID: 17555647
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
